摘要
目的探讨在缺铁性贫血(IDA)的鉴别诊断中检测网织红细胞血红蛋白(Ret-He)水平的临床意义。方法选取我院收治的贫血患者95例,将50例IDA患者作为IDA组,45例其他类型的贫血患者作为贫血组,另从健康人群中选取50例作为对照组。分别检测三组的常用红细胞参数及Ret-He水平,评价Ret-He水平检测对IDA鉴别诊断的意义。结果三组的血红蛋白浓度(Hb)、红细胞平均体积(MCV)、红细胞平均血红蛋白含量(MCH)、Ret-He水平比较,差异有统计学意义(P<0.05);贫血组的Hb水平明显低于对照组(P<0.05);IDA组的Ret-He、MCV、MCH、Hb水平均低于对照组和贫血组(P<0.05);Ret-He水平检测诊断IDA的灵敏度、特异度分别为96.00%、89.47%。结论 Ret-He水平检测对于IDA的诊断及鉴别具有较高的临床价值,在临床具有较好的应用前景。
Objective To investigate the clinical significance of reticulocyte hemoglobin（Ret-He） level detection in the differential diagnosis of iron deficiency anemia（IDA）. Methods Ninety-five cases of anemia patients were selected in our hospital, including 50 cases of IDA patients which were selected as the IDA group, the remaining 45 cases of other types of anemia patients which were collected as the anemia group, and 50 healthy people which were selected as the control group.The red blood cell parameters and Ret-He contents of the three groups were detected respectively, and the significance of Ret-He level detection in the differential diagnosis of IDA was evaluated. Results The hemoglobin concentration（Hb）,mean corpuscular volume（MCV）, mean corpuscular hemoglobin content（MCH） and Ret-He levels were statistically different among the three groups（P0.05）. The Hb level in the anemia group was lower than that in the control group（P〈0.05）. The levels of Ret-He, MCV, MCH and Hb in the IDA group were lower than those in the control group and the anemia group（P〈 0.05）. The sensitivity and specificity of Ret-He in the diagnosis of IDA were 96.00%, 89.47%respectively. Conclusion The detection of Ret-He level has high clinical value for the diagnosis and differential diagnosis of IDA, and it has a good prospect in clinical application.
作者
蔡文娟
张晓敏
CAI Wen-juan;ZHANG Xiao-min(Hematology Department,the Hospital of Qishan County,Baoji 722400,Chin)
出处
《临床医学研究与实践》
2018年第16期109-110,共2页
Clinical Research and Practice
