摘要
目的:探讨宫腔镜电切术应用右美托咪定联合七氟烷吸入麻醉的效果。方法:回顾性选取2016年12月至2017年12月湖北省京山县人民医院收治的拟行宫腔镜电切术治疗的妇科疾病患者108例作为研究对象,按麻醉方案不同分为观察组和对照组,每组54例。对照组患者行七氟烷吸入麻醉,观察组患者在对照组的基础上加用右美托咪定进行麻醉。于麻醉前(T_1)、术中(T_2)、术毕清醒时(T_3)、清醒后10 min(T_4)观察两组患者血压、心率及呼吸频率,比较两组患者的麻醉起效时间、麻醉苏醒时间、Ramsay评分、警觉/镇静观察评分、视觉模拟评分及不良反应发生情况的差异。结果:对照组患者T_2时的收缩压、舒张压及呼吸频率明显低于T_1时,观察组患者T_2、T_3及T_4时的心率明显低于对照组同期,观察组患者T_2时的呼吸频率明显低于对照组,上述差异均有统计学意义(P<0.05);两组患者麻醉起效时间、麻醉苏醒时间的差异均无统计学意义(P>0.05);术后,观察组患者Ramsay评分、警觉/镇静观察评分及视觉模拟评分明显优于对照组,差异均有统计学意义(P<0.05);观察组患者术后不良反应发生率为11.11%(6/54),明显低于对照组的29.63%(16/54),差异有统计学意义(P<0.05)。结论:宫腔镜电切术应用右美托咪定联合七氟烷吸入麻醉的效果显著,能减少患者术中血流动力学波动,镇静、镇痛效果良好,麻醉不良反应少。
OBJECTIVE： To probe into the anesthesia effects of dexmedetomidine combined with sevoflurane inhalation in hysteroscopic resection. METHODS： 108 patients with gynecologic diseases accepting hysteroscopic resection admitted into Hubei Jingshan County People＇s Hospital from Dec. 2016 to Dec. 2017 were retrospectively selected and divided into observation group and control group via different anesthesia regimen,with 54 cases in each.The control group was given sevoflurane inhalation anesthesia,while the observation group additionally received dexmedetomidine based on the control group. The blood pressure,heart rate and respiratory rate of two groups in preanesthesia（ T1）,intra-operative（ T2）,awaking after operation（ T3） and 10 min after awaking（ T4） were observed;and the onset time of anesthesia,recovery time,Ramsay score,alert/sedation score,visual analogue scale（ VAS） and incidence of adverse drug reactions of two groups were compared. RESULTS： The systolic blood pressure,diastolic blood pressure and respiratory rate of control group in T2 was significantly lower than that in T1. The heart rate of observation group in T2,T3 and T4 was significantly lower than that of the control group; the respiratory rate of observation group in T2 was significantly lower than that of control group,with statistically significant differences（ P〈0. 05）. There was no statistically significance between two groups in the onset time of anesthesia and recovery time（ P〉0. 05）. After operation,the Ramsay score,alert/sedation score,VAS of observation group were significantly better than those of control group,with statistically significant difference（ P〈0. 05）. The incidence of adverse drug reactions of observation group was 11. 11%（ 6/54）,significantly lower than that of control group（ 29. 63%,16/54）,with statistically significant difference（ P〈0. 05）. CONCLUSIONS： The anesthesia effects of dexmedetomidine combined with sevoflurane inhalation in hysteroscopic resection is signi
作者
黄文杰
胡继红
HUANG Wenjie;HU Jihong(Dept.of Anesthesiology,Hubei Jingshan County People＇ s Hospital,Hubei Jingshan 431800,China)
出处
《中国医院用药评价与分析》
2018年第6期771-773,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
宫腔镜电切术
右美托咪定
七氟烷
麻醉效果
Hysteroscopic resection
Dexmedetomidine
Sevoflurane
Anesthesia effects
