摘要
目的:观察孕前中药辨证论治对早期自然流产患者再孕结局的影响。方法:将符合入选标准的160例有早期自然流产史的患者随机分为观察组和对照组。观察组于备孕前3个月服用中药,同时服用维生素E、叶酸;对照组备孕前3个月仅服用维生素E和叶酸。确定妊娠后,两组患者均用中药、黄体酮胶丸、绒毛膜促性腺激素等安胎治疗。观察两组患者妊娠时的症状及血清性激素水平,追踪妊娠结局。结果:观察组97例,治疗有效率(88.7%)显著高于对照组(73.8%),孕早期先兆流产症状积分均低于对照组,孕早期血清绒毛膜促性腺激素、孕酮及雌二醇水平均高于对照组(均P<0.05)。结论:孕前辨证论治可显著改善早期自然流产患者妊娠结局。
Objective：To observe the effect of traditional Chinese medicine（TCM）syndrome differentiation and pretreatment on pregnancy outcomes of women with history of early spontaneous abortion.Methods：160 women with history early spontaneous abortion were divided into study group and control group randomly.The pretreatment of TCM started given to women who planned to pregnancy three months before in study group,and vitamin E and folic acid were also given.For the women in control group,vitamin E and folic acid were given only at the same time.After pregnancy,all women in both groups had been given Chinese medicine,progesterone soft capsules,and chorionic gonadotropin（HCG）HCG for preventing miscarriage.The symptoms during gestation,serum levels of HCG,progesterone（P）and estradiol（E_2）were compared between the two groups.Besides,the pregnancy outcomes of all women were also followed up.Results：The effective rate of women in study group（88.7% in 97 cases）was significant higher than that of women（73.8%）in control group（P〈0.05）.The symptom scores of threatened abortion in the first trimester early pregnancy of women in study group（50.5 feb）was significant lower than that of women（73.7 feb）in control group（P〈0.05）.The level of serum HCG,progesterone and estradiol of the first trimester early pregnant women in study group were significant higher than those of women in control group（P〈0.05）.Conclusion：TCM syndrome differentiation and pretreatment of for women who want to pregnancy can significantly improve the pregnant outcomes of women with history spontaneous abortions in the first trimester pregnancy.
作者
许金晶
吴育宁
张庆
赵葳
XU Jinjing;WU Yuning;ZHANG Qing;ZHAO Wei(Beijing Tongrentang Hospital of Traditional Chinese Medicine,Beijing,100051;Beijing Hospital of TCM Affiliated to Capital University of Medical Science)
出处
《中国计划生育学杂志》
2018年第7期574-577,共4页
Chinese Journal of Family Planning
基金
2015年度北京市科学技术协会金桥工程种子资金(ZZ15032)
关键词
辨证论治
孕前治疗
早期自然流产
妊娠结局
Syndrome differentiation and treatment
Treatment before pregnant
Spontaneous abortionin the first trimester pregnancy
Pregnancy outcomes
