摘要
目的:比较米索前列醇不同给药途径终止8~16周妊娠的有效性、安全性。方法:选取2016年12月-2017年6月本院终止妊娠的180例患者,按照给药方式不同分为阴道组(85例)与口服组(95例),比较两组用药成功情况及不良反应。结果:米索前列醇阴道用药和口服用药的成功率比较差异均无统计学意义(P>0.05)。阴道给药组不良反应发生率低于口服组(P<0.05)。结论:米非司酮配伍米索前列醇对于终止8~16周活胎妊娠或稽留流产均安全有效,米索前列醇阴道用药优于口服用药。
Objective：To compare the efficacy and safety of Misoprostol for the termination of 8-16 weeks of pregnancy.Method：A total of 180 pregnant women in our hospital from December 2016 to June 2017 were randomly divided into vaginal group of 85 cases and oral group of 95 cases according to different administration routes.Result：There was no significant difference in the effective rate of Misoprostol in the two groups（P〉0.05）.The number of Misoprostol and the time of pregnancy substance excretion in the vagina group were all less than those in the oral group,the incidence of adverse reactions in the vaginal group was lower than that in the oral group（P〈0.05）.Conclusion：Mifepristone and Misoprostol for termination of 8-16 week pregnancy or abortion are safe and effective.Misoprostol through vaginal administration better than oral administration.
作者
蔡婕
骆亚平
CAI Jie;LUO Yaping(Xiamen Maternal and Child Health Care Hospital,Xiamen 361000,China)
出处
《中国医学创新》
CAS
2018年第10期124-127,共4页
Medical Innovation of China
