摘要
目的：通过临床观察探讨自拟安眠方治疗2型糖尿病合并失眠的临床疗效。方法：把符合纳入标准的2型糖尿病合并失眠的患者共60例,按照就诊时间的顺序随机分为治疗组和对照组。通过中医证候量表、匹兹堡睡眠质量指数量表和右佐匹克隆进行疗效比较,治疗前后的自身对照以及治疗后组间比较;观察安眠方对患者夜间睡眠质量的改善情况。结果：治疗组治疗前后症状改善情况与对照组比较P〈0.05,有显著差异;治疗组与对照组临床疗效比较P〉0.05,无统计学差异,说明治疗组与对照组比较在调整睡眠时间方面无统计学差异。两组中医症状疗效比较P〈0.05,有显著差异;治疗组与对照组治疗前后PSQI总积分比较P〈0.05,有显著差异。所有入选患者治疗前后均进行血、尿常规,肝、肾功及心电图检查,结果无不良事件发生。结论：安眠方治疗消渴合并阴虚阳亢型不寐疗效显著。
Objective：To explore the clinical efficacy of self-designed sleeping prescription for the treatment of type 2 diabetes mellitus and insomnia. Methods：A total of 60 patients with type 2 diabetes mellitus with insomnia were classified into treatment group and control group. Through the TCM syndrome scale,the therapeutic efficacy of the Pittsburgh sleep quality index scale and the dexzopiclone were compared,and the comparison between the patients before and after treatment and the comparison between groups after treatment;To observe the improvement of the sleeping quality of the sleeping side. Results：The improvement of symptoms before and after treatment in the treatment group compared with the control group was P〈0.05,with significant difference. The clinical efficacy of the treatment group and the control group was compared with P〉0.05,without statistical difference,indicating that there was no statistical difference in the adjustment of sleep time between the treatment group and the control group. The efficacy of the two groups of TCM symptoms was more than P〈0.05,with significant difference. The total score of PSQI in the treatment group and the control group was P〈0.05,with significant difference. Blood,urine routine,liver,renal function and electrocardiogram examination were performed before all patients were enrolled,and no adverse events occurred. Conclusion：The therapeutic effect of sleeping prescription in the treatment of dipsia and hyperactivity of Yang due to Yin deficiency was significant.
作者
王亚茹
于世家
WANG Yaru;YU Shijia(Liaoning University of Traditional Chinese Medicine, Shenyang 110847, Liaoning, China)
出处
《辽宁中医药大学学报》
CAS
2018年第6期145-148,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
辽宁省教育厅重点实验室基础研究项目(LZ2014043)
关键词
安眠方
阴虚阳亢
不寐
临床观察
Anmian Decoction
Yin deficiency and Yang hyperactivity
insomnia
clinical observation
