摘要
肝移植是目前公认的治疗终末期肝病的惟一有效手段。自身免疫性肝病(AILD)主要包括自身免疫性肝炎(AIH)、原发性胆汁性胆管炎(PBC)、原发性硬化性胆管炎(PSC),其肝移植适应证与其他急、慢性肝病类似。尽管AILD患者行肝移植术预后良好,但术后复发较为常见,影响了患者的术后管理和移植物的存活率。此外需注意的是,非AILD肝移植患者术后会新发AIH。本文就AILD的肝移植适应证和预后作一概述。
Liver transplantation is a well accepted treatment for patients with end-stage liver disease. The indications of liver transplantation for autoimmune liver diseases such as autoimmune hepatitis,primary biliary cholangitis,and primary sclerosing cholangitis are similar to that with other acute or chronic liver diseases. Despite liver transplantation has a favorable overall outcome in these patients,the recurrence of autoimmune liver diseases is relatively common and challenges remain in terms of the management and survival of graft. It should be noted that de novo autoimmune hepatitis can arise in patients transplanted for non-autoimmune liver diseases. In this article,the indications and outcomes of liver transplantation in patients with autoimmune liver diseases were discussed for the better understanding of liver transplantation in this setting.
作者
孙汉勇
夏强
SUN Hanyong, XIA Qiang.(Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai （200127）)
出处
《胃肠病学》
2018年第5期300-304,共5页
Chinese Journal of Gastroenterology
