摘要
目的比较超声造影（CEUS）与增强CT（CECT）对病灶最大径≤2cm转移性肝癌（MLC）的诊断价值。方法选取中山大学附属第一医院确诊为MLC且病灶最大径≤2cm的患者69例，回顾性分析CEUS及CECT对MLC的检出率、诊断信心及其增强模式，并通过诊断性试验比较两种影像学检查对最大径≤2cm MLC的诊断价值。结果CEUS、CECT对69例最大径≤2cm MLC检出病灶个数为0个、1个、2个和多个的例数分别为0例（0％）、41例（59．42％）、13例（18．84％）、15例（21．74％）以及9例（13．04％）、29例（42．03％）、13例（18．84％）、18例（26．09％），CEUS、CECT检出例数分别为69例（100．0％）和60例（86．96％），差异有统计学意义（P=0．006）；对非单发病例病灶检出率两者差异无统计学意义（P=0．409）；69例最大径≤2cm MLC中CEUS、CECT表现典型的病例分别为56例（81．16％）、29例（42．03％）（P〈0．001）；CEUS和CECT对MLC的诊断信心为3、4和5级的病例数分别为3例（0．04％）、11例（15．94％）、55例（79．71％）以及19例（27．54％）、20例（2899％）、20例（28．99％）；cEus、cEcT对最大径≤2cm MLC的诊断敏感性分别为100％（69／69）、85．51％（59／69），差异有统计学意义（P=0．001）。结论CEUS对最大径≤2cm MLC的检出率和诊断价值优于CECT，但在非单发病例病灶检出率方面两者无差异，CEUS在最大径≤22cm MLC的诊断方面具有重要的临床价值。
Objective To compare the diagnostic performance of contrast-enhanced ultrasound （CEUS） with contrast enhanced computed tomography （CECT） for the maximum diameter ≤ 2 cm metastatic liver cancer （MLC）. Methods Sixty nine pathologically diagnosed MLC patients （maximum diameter 42 cm） were retrospectively recruited. The lesion detection rate, diagnostic confidence and enhancement pattern of CEUS and CECT for MLC were analyzed. Diagnostic value of CEUS and CECT for MLC were evaluated and compared by using diagnostic test. Results The cases of 0, 1,2, multiple lesions detected by CEUS and CECT in these 69 patients with 42 cm MLC were 0 case （0%）, 41 cases（59.42 % ）, 13 cases（18.84%）,15 cases（21.74%） and 9 cases（13.04%）,29 cases（42.03%）, 13 cases（18.84%）,18 cases （26.09 % ）, respectively. The positive cases detected by CEUS and CECT were 69 eases （ 100 % ） and 60 cases（86.96%） respectively, with a statistically significant difference between the two groups （P = 0.006）. However, for the detection rate of non-single-lesion cases, there was no statistical difference between CEUS and CECT （P = 0.409）. The cases showed typical manifestation in CEUS and CECT were 56 cases（81.16%）and 29 cases（42.03%）（P〈0.001）. The cases with diagnostic confidence level of 3,4, 5 in CEUS were 3 cases（0.04%）,11 cases（15.94%）,55 cases（79.71 %）,and those of CECT were 19 cases （27.54 % ）, 20 cases （ 28.99 % ）, 20 cases （28.99 % ）, respectively. The diagnostic sensitivity of CEUS andCECT for ≤2 cm MLC were 100% （69/69） and 85.51% （59/69）, with statistically significant difference （ P = 0. 001）. Conclusions The lesion detection rate and diagnostic value of CEUS for the maximum diameter ≤2 cm MLC might be superior to that of CECT, but the detection rate shows no significant difference in the non-single-lesion cases. CEUS has important clinical value in the diagnosis of ≤2 cm MLC.
作者
黄汝哨
林晋华
刘丹
谢晓燕
吕明德
林满霞
Huang Rushao;Lin Jinhua;Liu Dan;Xie Xiaoyan;Lyu Mingde;Lin Manxia(Department of Medical Ultrasonics, Longyan First Affiliated Hospital, Fujian Medical University, Longyan, Fujian 364000, Chin)
出处
《中华超声影像学杂志》
CSCD
北大核心
2018年第6期486-490,共5页
Chinese Journal of Ultrasonography
关键词
超声造影
转移性肝癌
增强CT
Contrast-enhanced ultrasound
Metastatic liver cancer
Contrast enhanced CT
