摘要
目的：观察消风止痒颗粒、氯雷他定片内服联合血液透析治疗尿毒症皮肤瘙瘁症的临床效果。方法：将医院收治的90例尿毒症皮肤瘙痒症患者随机分为对照组和观察组患者各45例。对照组患者给予氯雷他定片内服联合血液透析治疗，观察组患者则在对照组基础上加用消风止痒颗粒口服治疗，连续治疗2周为疗程。比较两组的临床疗效。评价治疗前后瘙瘁积分，监测血钙、血磷、血肌酐、尿素氮等生化指标变化。结果：观察组疗效高达91．1％，显著高于对照组的疗效73．3％（P〈0．05）；经治疗后，观察组患者的皮肤瘙痒程度改善显著优于对照组，其瘙痒积分均显著低于对照组（P〈0．05）；且观察组的血钙水平显著高于对照组，血磷、血肌酐、尿素氮等水平则显著低于对照组（P〈O．05）。结论：消风止痒颗粒、氯雷他定片内服联合血液透析治疗尿毒症皮肤瘙痒症临床效果肯定，利于改善皮肤瘙痒症状，提高肾功能，凸显出中西医结合治疗尿毒症并发症的优势与特点，值得临床推广运用。
Objective：To investigate the clinical effect of treating itchy skin of uremia patients with Xiaofeng Zhiyang Particles, Loratadine Tablets and hematodialysis. Methods ： Ninety cases were randomly divided into a control group of 45 cases and an observation group of 45 cases. Patients in the control group were treated with Loratadine Tablets and hemato- dialysis while those in the observation group were treated with Xiaofeng Zhiyang Particles on the basis of control group. The research was aimed at evaluating the effectiveness by comparing its itching integral and monitoring the blood calcium, blood phosphorus, blood creatinine, urea nitrogen and other biochemical indexes. Results ： The efficiency of patients in the observation group was 91.1%, which was higher than that of the control group（73.3% ） （P 〈0.05）. After treatment, the degree of itchy skin for patients in the observation group was significantly better than that of the control group, and the itch score was significantly lower than that in the control group （ P 〈 0. 05 ）. The blood calcium levels of the observation group were significantly higher than those of the control group, and the levels of blood phosphorus, blood creatinine and urea nitrogen were significantly lower than those in the control group（ P 〈 O. 05 ）. Conclusion：Treating itchy skin of ure- mia patients with Xiaofeng Zhiyang Particles, Loratadine Tablets and hematodialysis has good effect. The treatment can improve skin itching and kidney function, highlight the advantages and characteristics of the combination of Chinese and Western medicine in treating uremia complications, worthy of further research and development.
作者
葛杰
GE Jie(Zhejiang Hospital, Hangzhou 310013, Zhejiang, China)
出处
《中华中医药学刊》
CAS
北大核心
2018年第6期1497-1499,共3页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省科技厅一般科技项目(2016141205)
