摘要
目的:观察在常规救治措施基础上加用葛根芩连微丸联合纳洛酮治疗急性酒精中毒的临床疗效。方法:选取84例急性酒精中毒患者,随机分为对照组和观察组各42例,2组均采用常规救治措施,对照组加用注射用盐酸纳洛酮,观察组加用葛根芩连微丸与注射用盐酸纳洛酮,观察并比较2组的临床疗效、格拉斯哥昏迷指数(GCS)评分、意识恢复正常时间、肢体运动功能恢复正常时间及临床症状消失时间等。结果:治疗后,观察组总有效率100%,与对照组的88.1%比较,差异有统计学意义(P<0.05)。2组GCS评分均较治疗前升高,差异均有统计学意义(P<0.05);观察组GCS评分高于对照组,差异有统计学意义(P<0.05)。观察组意识恢复正常时间、肢体运动功能恢复正常时间及临床症状消失时间均较对照组缩短,差异均有统计学意义(P<0.05)。结论:在常规救治措施基础上加用葛根芩连微丸与注射用盐酸纳洛酮治疗,可使急性酒精中毒患者的意识、肢体功能等在较短的时间内逐步恢复,达到了快速醒酒、提高临床疗效的目的。
Objective：To observe the clinical effect of Gegen Qinlian Weiwan combined with naloxone based on the routine treatment for acute alcoholism.Methods：Selected 84 cases of patients with acute alcoholism,and divided them into the observation group and the control group randomly,42 cases in each group.Both groups received the routine treatment,and the control group was additionally given naloxone hydrochloride for injection,while the observation group was additionally given Gegen Qinlian Weiwan combined with naloxone hydrochloride for injection.Observed and compared the clinical effect,Glasgow coma scale（GCS）scores,the time for the consciousness returning to normal,the time for limb motor function returning to normal and the symptom disappearance time in both groups.Results：After treatment,the total effective rate was 100%in the observation group and 88.1%in the control group,difference being significant（P〈0.05）.GSC scores in both groups were higher than those before treatment,difference being significant（P〈0.05）;GCS scores in the observation group were higher than those in the control group,differences being significant（P〈0.05）.The time for the consciousness returning to normal,the time for limb motor function returning to normal and the symptom disappearance time in the observation group were respectively shorter than those in the control group,differences being significant（P〈0.05）.Conclusion：The additional application of Gegen Qinlian Weiwan combined with naloxone based on the routine treatment can make the consciousness and limb function of patients gradually recover in a comparatively short time,thus to reach the goal of quickly sobering up and promoting the clinical effect.
出处
《新中医》
CAS
2018年第6期90-92,共3页
New Chinese Medicine
