摘要
目的:观察参芪瓜蒌半夏薤白汤加减在治疗冠心病PCI术(经皮冠状动脉介入术)后患者再发心绞痛方面的临床应用疗效。方法:将100例行首次PCI治疗后仍有心绞痛发作的患者,随机分为2组,均给予西药标准治疗。对照组50例,单纯应用西药常规治疗,合并其他疾病者可继续服用对症药物;治疗组50例,在对照组治疗基础上加用参芪瓜蒌半夏薤白汤加减治疗。2组治疗期为1个月,1个月后记录2组临床疗效,对比2组治疗前后SAQ量表评分、中医证候疗效情况、治疗前后心绞痛疗效、治疗前后硝酸甘油片用量情况以及治疗前后血脂情况。结果:2组治疗后,治疗组SAQ量表评分改善各项均优于对照组,2组之间差异有统计学意义(P<0.05)。中医证候疗效情况:治疗组总共有效率96%,对照组总有效率74%,2组之间差异有统计学意义(P<0.01)。心绞痛疗效:治疗组总共有效率100%,对照组总有效率90%,2组之间差异有统计学意义(P<0.01)。硝酸甘油片用量情况:治疗组总共有效率90%,对照组总有效率70%,2组之间差异有统计学意义(P<0.01)。血脂指标变化情况:治疗组的TG、CHOL、LDL-C水平显著低于对照组,治疗组的HDL-C水平显著高于对照组,2组之间差异有统计学意义(P<0.05)。结论:参芪瓜蒌半夏薤白汤加减治疗冠心病PCI术后患者心绞痛再发方面疗效肯定。
Objective： To observe the effect of Shenqi Gualou Banxia Xiebai decoction with therapeutic combina- tion cutting in treatment of angina pectoris recurrence in patients with coronary heart disease after PCI. Methods： 100 patients with angina pectoris attacks after the first PCI treatment were randomly divided into 2 groups, and they were given standard western medicine treatment. The control group consists of 50 cases with application of the conventional western medicine treatment, patients combining with other diseases can continue to take symptomatic drug; the treat- ment group consists of 50 patients, add the Shenqi Gualou Banxia Xiebai decoction with therapeutic combination cut- ting to the basic western medicine treatment. The treatment period of both groups were 1 months, record the clinical efficacy of the two groups 1 months later, and compared two groups＇ data before and after treatment, including SAQ scale, TCM syndrome scores, angina pectoris recurrence, nitroglycerin tablets usage, and blood fat level. Results： After treatment, every item in the treatment groups＇ SAQ scale was superior to the control group, and the difference between the two groups is statistically significant（P〈0.05）. The TCM syndrome scores： the total effective rate of the treatment group was 96%, and the total effective rate of the control group was 74%, the difference between the two groups was statistically significant（P〈0.01）. Curative effect of angina pectoris. The total effective rate of the treatment group was 100%, and the control group＇ s total effective rate was 90%. The difference between the two groups was statistically significant（P〈0.01）. Nitroglycerin Tablets dosage： the total effective rate of the treatment group was 90%, and the total effective rate of the control group was 70%. The difference between the two groups was statistically significant（P〈0.01）. Changes of blood lipid indexes： The levels of TG, CHOL and LDL-C in the treatment group were significantly lower than those
作者
敖玉涵
张明雪
王秭萱
AO Yuhan;ZHANG Mingxue;WANG Zixuan(Affiliated Liaoning University of Traditional Chinese Medicine, Liaoning Shenyang 110000, China;Hospital of Liaoning University of Traditional Chinese Medicine, Liaoning Shenyang 110000, China;Hospital of Liaoning Province Armed Police Corps, Liaoning Shenyang 110000, China)
出处
《中医药临床杂志》
2018年第5期912-916,共5页
Clinical Journal of Traditional Chinese Medicine
关键词
PCI术后
心绞痛
参芪瓜蒌半夏薤白汤
中药
PCI postoperative
Angina
Shenqi Gualou Banxia Xiebai decoction
Traditional Chinese Medicine
