摘要
目的了解渝北区妇女HPV感染率、基因亚型和年龄的分布情况。方法采用导流杂交法检测1181例女性宫颈脱落细胞,对其进行HPV基因亚型检测。结果 1181例标本中,感染数215例,感染率18.20%,高危亚型居前五位的依次为52、16、39、18和58型;高危型HPV感染率高于低危型,单一感染率高于多重型感染(P<0.05);各年龄组感染无显著性差异(P>0.05)。结论 HPV感染具有年轻化趋势,HPV基因分型检测对疫苗的制备与宫颈癌的防治有指导意义。
Objective To study the situation of human papilloma virus（HPV） infection rate, genotype and age distribution of Yubei District women. Methods A total of 1181 cervical samples collected from women attending cervical screening were tested by Flow-through hybridization. Results Total of 215（18.20%）women were HPV positiveamong the 1181 patients.The high risk hy potype of HPV, for example, HPV52, HPV16, HPV39, HPV18 and H PV58; the high-risk HPV infection rate is higher than the low-risk type and Single infection rate is higher than multiple heavy infections（P〈0.05）; there was no significant difference in infection between age groups（P〉0.05）. Conclusion Human papilloma virus infection has a younger trend, the detection of human papillomavirus genotyping is of guiding significance for the preparation of vaccines and the prevention and treatment of cervical cancer.
作者
李琼
肖时超
LI Qiong, XIAO Shi-chao(Department of Clinical Laboratory, Yubei District People＇s Hospital, Chongqing 401120, Chin)
出处
《中国医药指南》
2018年第10期9-10,共2页
Guide of China Medicine
基金
重庆市渝北区科技化项目(编号2016(社)03)
关键词
人乳头瘤病毒
基因分型
疫苗制备
宫颈癌
Human papillmavirus
Gene subtypes
Vaccine preparation
Cervical cancer
