摘要
目的：基于孙伟教授＂肾虚湿瘀＂理论,益肾清利活血方治疗CKD 5期患者,延缓其进入透析时间的疗效观察。方法：100例苏州市中医医院门诊及病房慢性肾脏病5期患者,中医辨证属肾虚湿瘀证患者,按照纳入标准和排除标准筛选的合格病例,基于＂真实世界＂原理,按患者意愿选择中医治疗＋基础治疗（治疗组）或单纯基础治疗（对照组）,各50例。结果：治疗组47例,治疗总有效率为87.23%;对照组48例,治疗总有效率为68.75%,治疗组的总有效率优于对照组（P〈0.05）;治疗组中医证候总积分总有效率95.7%,明显高于对照组的77.1%,治疗组的总有效率优于对照组（P〈0.05）;治疗组Scr、e GFR前后比较有统计学意义（P〈0.05）,BUN前后比较无统计学意义（P〉0.05）;对照组治疗后BUN、Scr与治疗前相比,均呈下降趋势,其差别均无统计学意义（P〉0.05）。结论：益肾清利活血方能增加CKD 5期肾虚湿瘀证患者的肾小球滤过率,延缓CKD 5期患者进入透析时间。
Objective ：Based on Professor SUN Wei＇s＂kidney deficiency and dampness stasis＂theory,Yishen Qingli Huoxue Decoction in the treatment of patients with stage CKD5,and to delay the time of dialysis. Methods ：100 patients of Suzhou hospital of traditional Chinese medicine outpatient and ward stage 5 chronic kidney disease,TCM is kidney deficiency and dampness and blood stasis syndrome patients,in accordance with the inclusion criteria and exclusion standard screening qualified cases,based on the＂real world＂principle,according to the wishes of patients choose Chinese medicine treatment plus basic treatment（treatment group）or basic treatment alone（control 50 cases in each group）. Results ：47 cases in the treatment group,the total effective rate was 87.23%;the control group of 48 cases,the total effective rate was 68.75%,the total efficiency of the treatment group than the control group（P〈0.05）;the treatment group TCM syndrome total score of the total efficiency of 95.7%,significantly higher than 77.1% in the control group,the total efficiency of the treatment group better than the control group（P〈0.05）;group Scr and e GFR before and after treatment were statistically significant（P〈0.05）,before and after BUN was not statistically significant（P〈0.05）;compared with the control group after treatment,BUN and Scr before treatment were decreased,the difference was not statistically significant（P〈0.05）. Conclusion ：Yishen Qingli Huoxue Decoction can increase the glomerular filtration rate in patients with CKD5 stage of kidney deficiency and dampness stasis syndrome,and delay the dialysis time of CKD5 patients.
作者
任燕
孙伟
段星星
REN Yan;SUN Wei;DUAN Xingxing(Suzhou Hospital of Traditional Chinese Medicine Appiliated to Nanjing University of Chinese Medicine, Suzhou 215009, Jiangsu, China;Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China;Jiangsu Province Traditional Chinese Medicine Hospital, Nanjing 210029, Jiangsu, China)
出处
《辽宁中医药大学学报》
CAS
2018年第5期153-156,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
苏州市中医医院院内课题(KY0145)
关键词
肾虚湿瘀
慢性肾脏病5期
疗效观察
kidney deficiency and dampness stasis
5 stage of chronic kidney disease
curative effect observation
