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地塞米松穴位注射结合常规疗法治疗突发性耳聋临床研究 被引量:16

Clinical study of dexamethasone acupoint Injection combined with conventional therapy for sudden deafness
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摘要 目的评价地塞米松穴位注射结合常规疗法治疗突发性耳聋的疗效。方法将符合入选标准的72例突发性耳聋患者采用随机数字表法分为2组,每组36例。在常规治疗基础上,观察组每2d穴位注射1次地塞米松磷酸钠注射液,共治疗5次;对照组前3d静脉滴注地塞米松磷酸钠注射液,后3d改为口服醋酸地塞米松片,共治疗6d。比较2组平均听力闽值变化及伴随症状的疗效。结果治疗后,观察组平均听力阈值[(49.64±20.10)dB比(70.44±21.60)dB,t=4.231]、对照组平均听力阈值[(49.25±20.80)dB比(65.64±22.30)dB,t=3.225]均低于同组治疗前(P〈0.05)。观察组耳呜有效率为85.3%(29/34)、对照组为73.5%(25/34),2组比较差异有统计学意义(Z=-2.109,P=0.035);观察组耳闷胀感有效率为92.6%(25/27)、对照组为82.7%(24/29),2组比较差异有统计学意义(Z=-2.109,P=0.035);观察组眩晕有效率为92.9%(13/14)、对照组为69.2%(9/13),2组比较差异有统计学意义(Z=2.136,P=0.033)。治疗后,观察组病程≤7d与〉7d的患者有效率分别为90.5%(19/21)、66.7%(10/15),对照组分别为73.9%(17/23)、46.2%(6/13),2组组内不同病程总有效率比较,差异均有统计学意义(Z观察组=-2.162,P=0.031;ZWJIf!m=1.991,P=0.046)。结论地塞米松穴位注射结合常规疗法可有效改善突发性耳聋患者的耳鸣、耳闷胀感、眩晕等伴随症状。 Objective To evaluate the efficacy of dexamethasone acupoint injection combined with conventional therapy for the paitents with sudden deafness. Methods A total of 72 patients with sudden deafness who met the inclusion criteria were randomly divided into 2 groups with 36 in each group. On the basis of conventional therapy, the observation group injected dexamethasone at acupoints; control group intravenous drip combined with oral dexamethasone. The average hearing threshold and the efficacy of symptoms between the 2 groups were compared. Results After treatment, the average hearing threshold of the observation group (49.64 ±20.10 dB vs. 70.44 ± 21.60 dB, t=4.231), and the control group (49.25 ± 20.80 dB vs. 65.64 ± 22.30 dB, t=3.225) were both significantly lower than those before treatment (P〈0.05), but there was no significant difference between the two groups after treatment (P〉0.05). The effective rate of tinnitus was 85.3% (29/34) in the observation group and 73.5% (25/34) in the control group, and there was significant difference between 2 groups (Z=-2.109, P=0.035). The effective rate of ear fullness was 92.6% (25/27) in the observation group and 82.8% (24/29) in the control group, and the difference between the two groups was statistically significant (Z=-2.109, P=-0.035). The effective rate of dizziness in the observation group was 92.9% (13/14), whild the control group was 69.2% (9/13), and the difference between the two groups was statistically significant (Z=-2.136, P=0.033). After treatment, the effective rates of the patients in the observation group of ≤7 days and 〉7 days were 90.5% (19/21) and 66.7% (10/15) respectively (Z=-2.162, P=0.031), while in the control group they were 73.9% (17/23) and 46.2% (6/13) respectively (Z=1.991, P=0.046). Conclusions The Dexamethasone acupoint injection combined with conventional therapy can effectively improve the accompanying symptoms such as tinnitus, ear fullness and verti
作者 漆小丽 沈峰 Qi Xiaoli;Shen Feng(Master of Grade 2015, Nanjing University of Chinese Medicine, Nanjing 210023, China Corresponding author." Shen Feng, TCM E.N.T. Department, Jiangsu Province Hospital of Traditional Chinese)
出处 《国际中医中药杂志》 2018年第5期406-409,共4页 International Journal of Traditional Chinese Medicine
关键词 突发性耳聋 穴位疗法 地塞米松 翳风 听宫 Sudden deafness Acupoint therapy Dexamethasone Point TE17(Y^feng) Point SI19(Tinggong)
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