摘要
目的观察病毒性脑膜炎患者引发癫痫持续状态的用药监护效果。方法选取2015年12月-2017年4月在医院诊治的病毒性脑膜炎患者引发癫痫持续状态86例,随机分为观察组和对照组各43例。对照组进行常规治疗,观察组在常规治疗的基础上进行用药监护,对比2组患者用药依从性、治疗效果和药物的不良反应情况。结果观察组患者的用药依从性评分为(76.48±12.36)分高于对照组的(58.73±10.92)分,总有效率为95.35%高于对照组的79.07%,不良反应发生率为9.30%低于对照组的34.88%,差异均有统计学意义(P<0.05)。结论对病毒性脑膜炎患者引发癫痫持续状态在常规治疗的基础上,进行用药监护,能显著提高患者的用药依从性和临床治疗效果,降低患者的药物不良反应发生率,值得进行临床推广。
Objective To analyze the medication monitoring effects of patients with status epilepticus induced by viral meningitis. Methods 86 patients with epileptic status caused by viral meningitis diagnosed and treated in hospital from December 2015 to April 2017 were randomly divided into observation group and control group with 43 cases each. Control group received routine treatment. Observation group performed medication monitoring on the basis of routine treatment. The medication compliance,therapeutic effect and adverse drug reactions were compared between two groups. Results The medication compliance score of observation group was(76. 48 ± 12. 36） points higher than(58. 73 ± 10. 92） points of control group,the total effective rate was 95. 35% higher than 79. 07% of control group,and the adverse reaction rate was 9. 30% lower than34. 88% of control group,the difference was statistically significant(P〈0. 05）. Conclusion In patients with viral meningitis cause status epilepticus,on the basis of conventional treatment,medication monitoring can significantly improve the patients＇ medication adherence and clinical therapeutic effect,decrease the rate of adverse drug reactions in patients with,is worth popularizing in clinical.
作者
梁小娇
林满秋
LIANG Xiaojiao;LIN Manqiu(Neurology, The People＇s Hospital of Xinyi City, Guangdong Province, Xinyi 525300, Chin)
出处
《临床合理用药杂志》
2018年第13期25-26,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
病毒性脑膜炎
癫痫持续状态
用药监护
Viral meningitis
Status epilepticus
Medication monitoring
