摘要
大豆异黄酮是一类具有多种生物活性的天然异黄酮,大豆苷元是其中一种,具有抗肿瘤、心脑血管保护、降血脂、抗骨质疏松、抗动脉粥样硬化及调节内分泌等多种作用,且大豆苷元的摄入与降低心脑血管疾病风险相关。本文从大豆苷元保护血管、大脑和心肌等方面进行综述,为深入开展大豆苷元对心脑血管疾病的防治作用研究、扩大大豆苷元临床应用提供参考。
Soy isoflavones are a category of natural isoflavones with various biological activities. Daidzein is an isoflavone compound,which exhibits many kinds of bioactivities,such as anti-tumor,cardio-cerebral vascular protection,blood lipid reduction,the anti-osteoporosis,anti-atherosclerosis and endocrine system regulation. In addition,daidzein intake is associated with reducing risk of cardio-cerebrovascular diseases. In this paper,we review the research progresses of daidzein in the prevention and treatment of cardiocerebrovascular diseases in terms of its protectire effect on blood vessels,brain and myocardium in order to provide a reference for further investigation on the prevention and treatment effect of daidzein on cardio-cerebrovascular diseases to expand its clinical application.
作者
韩晓乐
滕晓涵
许怡
杨骏
谢燕
HAN Xiao-le1,2, TENG Xiao-han1, XU Yi1, YANG Jun2, XIE Yan1(1. College of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; 2. Shanghai Huangpu District Xiangshan Hospital of TCM Shanghai 200020, Chin)
出处
《国际药学研究杂志》
CSCD
北大核心
2017年第12期1093-1097,1124,共6页
Journal of International Pharmaceutical Research
基金
上海市人才发展资金项目(201565)
上海中医药大学第九批大学生科创项目
关键词
大豆苷元
防治
心脑血管疾病
黄酮类化合物
daidzein
prevention and treatment
cardiovascular and cerebrovascular diseases
flavonoid compounds
