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异丙酚联合七氟醚麻醉在小儿斜疝手术中的应用效果分析 被引量:2

Analysis of the anesthesia effect of propofol combined with sevoflurane in children with indirect inguinal hernia
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摘要 目的:探讨异丙酚联合七氟醚麻醉在小儿斜疝手术中的应用效果。方法:2016年1月~2017年1月选择在我院进行诊治的斜疝患儿180例作为研究对象,根据随机信封抽签原则分为观察组与对照组各90例,两组都给予腹股沟疝囊高位结扎术,对照组给予基于异丙酚的全身麻醉,观察组给予基于异丙酚联合七氟醚的全身麻醉,对比两组麻醉拔管后20min内躁动发生率、苏醒时间、苏醒后不良反应发生率、平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(Sp O2)指标。结果:所有患儿顺利完成手术与麻醉,观察组麻醉拔管后20min内躁动发生率为2.2%,对照组为8.9%,观察组麻醉苏醒后躁动发生率明显低于对照组(P<0.05)。观察组苏醒后的低氧血症、喉痉挛、返流误吸等不良反应发生率为7.8%,对照组为8.9%,两组对比差异无统计学意义(P>0.05)。观察组苏醒时间为(5.24±1.02)min,对照组苏醒时间为(8.51±2.94)min,差异存在统计学意义(t=9.9688,P=0.0000)。观察组HR平均检测结果、MAP平均检测结果与对照组对比,差异具有统计学意义(t=26.6516,35.1568,P=0.0000,0.0000),对Sp O2检测发现,两组SpO_2<95%的概率差异存在统计学意义(X^2=7.8429,P=0.0051)。结论:异丙酚联合七氟醚麻醉在小儿斜疝手术中的应用能有效防止术后躁动,且不会增加术后不良反应的发生,值得推广应用。 Objective:To investigate the anesthesia effect of propofol combined with sevoflurane in children with indirect inguinal hernia.Methods:From January 2016 to January 2017,180 children with indirect indirect hernia in our hospital were selected as the subjectsand divided into observation group and control group according to the random envelope drawing principle,90 cases in each group. Twogroups of children were given high ligation of inguinal hernia sac,the control group received general anesthesia based on propofol,theobservation group received general anesthesia based on propofol combined with sevoflurane. The incidence of restlessness in 20min afterextubation,recovery time,recovery rate of adverse reactions,mean arterial pressure (MAP) ,heart rate (HR)and pulse oxygensaturation (SpO2) were compared between the two groups. Results:All the children completed the operation and anesthesiasuccessfully,the incidence of restlessness in 20min after extubation in observation group was 2.2%,and control group was 8.9%,theincidence of restlessness in the observation group after anesthesia recovery was significantly lower than that in the control group (P〈0.05) . The incidence of adverse reactions such as hypoxemia,laryngeal spasm,reflux and aspiration was 7.8% after the recovery of theobservation group,the control group was 8.9%,there was no statistical difference between the two groups (P〉0.05) . The recovery time ofthe children in the observation group was(5.24依1.02) min,the control group was(8.51依2.94) min,there is statistically significant (t=9.9688, P=0.0000) . There is statistically significant between two groups in the average HR test result and the MAP average test result (t=26.6516, 35.1568, P=0.0000, 0.0000) . The SpO2 test showed that the difference in the probability of SpO2 〈 95% between the two groupswas statistically significant (X2=7.8429, P=0.0051) . Conclusion:Application of propofol combined with sevoflurane in children withindirect inguinal hernia
作者 郭林艳 Guo Linyan(################)
出处 《北方药学》 2018年第6期8-9,共2页 Journal of North Pharmacy
关键词 异丙酚 七氟醚麻醉 小儿 斜疝 Propofol Sevoflurane Children Indirect inguinal hernia
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