摘要
目的探讨了接受体外受精-胚胎移植(IVF-ET)技术的卵巢高反应患者使用拮抗剂方案的安全性。方法共分析3例卵巢高反应者,均使用拮抗剂方案行超促排卵,观察患者是否发生中-重度卵巢过度刺激综合征(OHSS)。结果 3例患者中有2例未发生OHSS,1例发生重度OHSS。结论在卵巢高反应患者中,应用拮抗剂方案并不能完全避免OHSS的发生。为了有效避免中-重度OHSS的发生,应该制定合适的Gn起始剂量,选择恰当的诱发排卵的药物和剂量。
Objective To evaluate the safety of gonadotropin-releasing hormone （GnRH） antagonist protocol for high ovarian responders during in vitro fertilization-embryo transfer （IVF-ET）. Methods GnRH antagonist protocol was used for three high ovarian responders. The incidence of moderate-severe ovarian hyperstimulation syndrome （OHSS） was observed. Results One case of moderate OHSS occurred in three patients. Conclusion Utilization of GnRH antagonist protocol can not absolutely prevent the occurrence of OHSS. Suitable starting doses of gonadotropins and appropriate trigger drugs should be used for avoiding the occurrence of moderate-severe OHSS.
作者
邢卫杰
欧建平
蔡柳洪
陶欣
孙丽
李涛
Xing Weijie;Ou Jianping;Cai Liuhong;Tao Xin;Sun Li;Li Tao(Center for Reproductive Medicine, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2018年第3期238-240,共3页
Chinese Journal of Reproduction and Contraception
关键词
卵巢高反应
拮抗剂方案
卵巢过度刺激综合征(OHSS)
High ovarian responders
gonadotropin-releasing hormone （GnRH） antagonist protocol
Ovarian hyperstimulation syndrome （OHSS）
