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不同剂量瑞舒伐他汀治疗急性ST段抬高型心肌梗死短期预后

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摘要 目的:分析不同剂量瑞舒伐他汀对急性ST段抬高型心肌梗死短期预后的影响。方法:选取2015年12月~2016年12月我院收治的急性心肌梗死患者140例,随机分为对照组和观察组,各70例。对照组予以5 mg/d瑞舒伐他汀治疗,观察组予以10mg/d瑞舒伐他汀治疗,两组均持续他汀治疗1个月。比较两组患者治疗前后血脂变化、心血管事件发生率和死亡率。结果:治疗前,两组患者血脂指标比较差异无统计学意义(P>0.05);治疗1个月后,观察组TC、LDL-C水平均明显低于对照组(P<0.05);两组治疗后的HDL-C水平比较差异无统计学意义(P>0.05);观察组随访期死亡率低于对照组(P<0.05);两组心血管不良事件发生率比较差异无统计学意义(P>0.05)。结论:给予急性ST段抬高型心肌梗死患者10 mg/d瑞舒伐他汀治疗,可有效提高降脂效果,降低死亡率,且不增加心血管事件发生率,值得临床推广应用。
作者 郭艳涛
出处 《实用中西医结合临床》 2018年第2期62-63,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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