摘要
目的探讨微创穿刺联合口服阿托伐他汀治疗慢性硬脑膜下血肿的临床疗效。方法慢性硬脑膜下血肿患者48例随机均分为两组:对照组患者使用微创穿刺治疗,观察组患者在此基础上加用阿托伐他汀口服(20mg/d,治疗1~3个月)。比较两组疗效。结果观察组总有效率与对照组相仿(95.8%vs.91.7%)(P>0.05);治疗后,观察组日常生活自理能力(ADL-Barthel)评分高于对照组(P<0.05),症状改善时间也早于对照组(P<0.05)。观察组并发症发生率和复发率低于对照组(8.3%vs.33.3%和0vs.20.8%)(P<0.05)。结论在微创穿刺的基础上,联合口服阿托伐他汀治疗可有效地降低慢性硬脑膜下血肿患者的并发症和复发率。
Objective To observe the efficacy of minimally invasive puncture combined with atorvastatin in treating chronic subdural hematoma. Methods Forty-eight patients with chronic subdural hematoma were randomized into two groups and treated with minimally invasive puncture combined with oral atorvastatin 20 mg/d for 1 to 3 months（group A, 24 cases） and minimally invasive puncture only（group B, 24 cases）. The efficacy was compared between two groups. Results The overall effectiveness rate of group A was similar to that of group B（95.8% vs. 91.7%） （P〉0. 05）. Compared to group B after treatment, group A had a higher ADL-Barthel score and shorter time for the symptom improvement（P〈0. 05）. The incidence rate and recurrence rate were lower in group A than those in group B（8.3% vs. 33.3% and 0 vs. 20.8%） （P〈0. 05）. Conclusion On the basis of minimally invasive puncture, combined with oral atorvastatin treatment can effectively reduce the incidence rate of complications and recurrence rate.
作者
王云峰
闫西刚
徐建林
庄敏杰
周志杰
WANG Yunfeng;YAN Xigang;XU Jianlin;et al(Department of Neurosurgery , Suzhou Wuzhong People ＇ s Hospital, Suzhou 215128, CHINA)
出处
《江苏医药》
CAS
2018年第4期416-418,共3页
Jiangsu Medical Journal
