摘要
目的研究角膜炎患者采用维生素C实施治疗的临床价值。方法选取在我院接受药物治疗的108例角膜炎患者,通过随机分组的形式将其分成对照组和治疗组,每组54例。对照组采用常规眼科用药方案实施治疗;治疗组在常规眼科用药方案基础上,加用维生素C实施治疗。比较两组患者角膜炎病情控制总有效率,用药原因所导致的不良反应,治疗后病情复发率,治疗前、后炎症因子相关指标水平的改善幅度。结果治疗组患者角膜炎病情控制总有效率为90.7%,高于对照组的66.7%(P<0.05);治疗组用药原因所导致的不良反应仅有3例,略多于对照组的2例,但无显著差异(P>0.05);治疗后治疗组复发率为7.4%,低于对照组为24.1%(P<0.05);治疗组治疗后炎症因子相关指标水平的改善幅度大于对照组(P<0.05)。结论角膜炎患者采用维生素C实施治疗,可以在短时间内控制炎症,缩短治疗时间,使疾病的治疗效果明显提高,防止病情在治疗后再次复发,且不会对安全性造成影响。
Objective To study the clinical value of vitamin C in the treatment of keratitis. Methods＇ A total of 108 cases of keratitis in our hospital were randomly divided into control group and treatment group, with 54 cases in each group. The control group was treated with routine ophthalmic medication, and the treatment group was treated with vitamin C on the basis of routine ophthalmic medication. The total effective rate of drug control, the adverse reactions caused by medication reasons, the recurrence rate after treatment and the level of inflammatory factors related indicators before and after treatment were compared between the two groups. Results＇ The total effective rate in the treatment group patients with ker- atitis was 90.7%, which was higher than 66.7% in the control group （P〈0.05）; the adverse reaction caused by drug in the treatment group only were 3 cases, slightly more than 2 cases in the control group, but it was no significant difference （P〉 0.05）; afler treatment, the recurrence rate of the treatment group was 7.4%, which was lower than 24.1% of the control group （P〈0.05）; the improvements of the indexes level of the inflammatory factors related in the treatment group were greater than those in the control group （P〈0.05）. Conclusion The implementation of vitamin C in the treatment of keratitis can control inflammation in a short time, shorten the treatment time, improve the therapeutic effect of the disease, prevent recurrence after treatment, and will not affect the safety.
作者
刘强
LIU Qiang(the People＇s Hospital of Ansai District, Yan＇an 717400, China)
出处
《临床医学研究与实践》
2018年第13期42-43,共2页
Clinical Research and Practice
关键词
角膜炎
维生素C
复发
keratitis
vitamin C
recurrence
