摘要
基质金属蛋白酶(MMPs)是Zn^(2+)家族依赖性蛋白酶,能够裂解所有细胞外基质(ECM)。ECM的降解参与喉癌的侵袭和转移,因此MMP-2在喉癌局部血管生成,侵袭转移等过程中可能发挥重要作用。
Matrix metalloproteinases（ MMPs） is a family of Zn2 ＋dependent protease,it is able to crack all the extracellular matrix（ ECM）. The degradation of ECM takes part in invasion and metastasis of laryngeal cancer,therefore MMP-2 may play an important role in local angiogenesis,invasion and metastasis.
作者
王博
田霖丽
刘鸣
Wang Bo;Tian Linli;Liu Ming(Department of Otorhinolaryngology First Ward Director, Head and Neck Surgery, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang Harbin 150086, China.)
出处
《现代肿瘤医学》
CAS
2018年第9期1470-1472,共3页
Journal of Modern Oncology
关键词
金属基质蛋白2
喉癌
综述
MMP - 2, laryngeal cancer, literature review
