摘要
目的探讨眼睑按摩联合聚乙二醇滴眼液治疗干眼症患者的临床效果。方法选取2015年10月~2017年10月吉林大学白求恩第一医院眼科收治的222例干眼症患者作为研究对象,根据就诊时间的差异分为两组。单一组(111例)单纯采用眼睑按摩治疗,联合组(111例)采用眼睑按摩联合聚乙二醇滴眼液治疗。分析比较两组患者的治疗效果,同时比较干预前后患者的干眼症状评分、泪膜破裂时间、角膜荧光素染色评分以及基础泪液分泌试验情况。结果联合组患者的总有效率为90.99%,与单一组(81.08%)比较,差异有统计学意义(P<0.05);治疗后,联合组患者的干眼症状评分为(3.12±0.25)分、泪膜破裂时间为(12.88±3.52)s、角膜荧光素染色评分为(1.05±0.90)分、基础泪液分泌试验为(6.38±1.14)mm/5 min,单一组干眼症状评分为(5.01±1.12)分、泪膜破裂时间为(8.33±1.99)s、角膜荧光素染色评分为(4.22±1.53)分、基础泪液分泌试验为(5.03±0.56)mm/5 min,两组比较,差异有统计学意义(P<0.05)。结论将眼睑按摩联合聚乙二醇滴眼液治疗干眼症,可达到较好的治疗效果,值得进一步推广应用。
Objective To explore the clinical effect of combining eyelid massage with Polyethylene Glycol eye drops in the treatment of xerophthalmia.Methods From October 2015 to October 2017,222 patients with xerophthalmia treated in First Hospital of Bethune in Jilin University were selected as the subjects,and divided into two groups according to the time of treatment.The single group（111 cases） were treated with eyelid massage alone,and the combined group（111 cases） were treated with eyelid massage combined with Polyethylene Glycol eye drops treatment.The therapeutic effects of the two groups were analyzed and compared.The scores of dry eye symptom,tear film rupture time,corneal fluoresce in staining score and basal tear secretion test were compared before and after intervention.Results The combined group had a total effective rate of 90.99%, which was significantly different from that of the single group（81.08%）（P〈0.05）.After treatment,the dry eye symptom score of the combined group was（3.12±0.25） points,membrane rupture time was（12.88±3.52） s,corneal fluorescein staining score was（1.05±0.90）,basal lacrimal secretion test was（6.38±1.14） mm/5 min.The dry eye symptom score of the single group was（5.01±1.12） scores,tear film rupture time was（8.33±1.99） s,corneal fluorescein staining score was（4.22±1.53） points,and basal tear secretion test was（5.03±0.56） mm/5 min.The difference was statistically significant between the two groups（P〈0.05）.Conclusion The combination of eyelid massage and Polyethylene Glycol eye drops for xerophthalmia treatment can achieve better therapeutic effect,which is worthy of further recommendation.
作者
周明波
王进
郝继龙
ZHOU Ming-bo;WANG Jin;O Ji-long(Department of Ophthalmology,the First Hospital of Bethune,Jilin University,Jilin Province,Chiangchun 130021,China;Department of Cataract,Purui Eye Hospital of Harbin,Heilongjiang Province,Harbin 150000,China)
出处
《中国当代医药》
2018年第11期111-113,共3页
China Modern Medicine
关键词
干眼症
眼睑按摩
聚乙二醇滴眼液
临床效果
Xerophthalmia
Eyelid massage
Polyethylene Glycol eye drops
Clinical effect
