摘要
目的探讨育龄期多囊卵巢综合征(PCOS)患者的临床特征及发病相关危险因素,初步构建PCOS危险因素Logistic回归模型。方法根据PCOS鹿特丹诊断标准,回顾性分析PCOS患者的临床特征,采用问卷调查法对131例PCOS患者以及同期作为对照的395例月经规律的非PCOS患者进行危险因素的采集,并通过病例对照研究分析PCOS发病的相关危险因素,建立Logistic回归模型。结果有8个危险因素进入回归模型。结论肥胖、初潮到月经规律所用时间>2年、患者母亲孕期营养不良、经常使用一次性塑料餐具或塑料水杯、缺乏运动、经常接触厨房油烟、居住地或工作地装修或装潢史、居住地周围石油化工厂或垃圾焚烧点是PCOS发病的危险因素,初步构建了具有较高诊断效能的回归模型。
Objective To investigate into the clinical characteristics and risk factors of reproductive age patients with polycystic ovary syndrome, and to construct a Logistic regression model of PCOS risk factors.Methods According to the diagnostic criteria of polycystic ovary syndrome in Rotterdam, the clinical features of PCOS patients were analyzed retrospectively. In the case-control study, 131 patients with PCOS were put into the case group and 395 non-PCOS patients with regular menstrual cycles were selected as the control.The Logistic regression model was established by analyzing the related risk factors of PCOS. Results Eight factors entered the regression model. Conclusion Risk factors of the incidence of polycystic ovary syndromeincluded obesity, menarche to menstrual regularity more than 2 years, patient mothers being malnourished during pregnancy, frequent use of disposable plastic tableware, lack of exercise, frequent exposure to kitchen fumes, residence or workplace decoration, residing near a petrochemical plant or waste incineration point. A regression model with high diagnostic efficiency was initially constructed for this kind of diagnosis.
作者
梁仲珍
王芳
裴泓波
陈莉
丁楠
蔡姣
Liang Zhong-zhen;Wang Fang;Pei Hong-bo;Chen Li;Ding Nan;Cai Jiao(Reproductive Medicine Center, The Second Hospital of Lanzhou University, Lanzhou 730030, China;Department of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, Lanzhou 730000, China)
出处
《兰州大学学报（医学版）》
CAS
2018年第2期46-53,共8页
Journal of Lanzhou University（Medical Sciences）
基金
兰州大学第二医院"萃英科技创新"计划项目(ynyjrckyzx2015-03-03)
