摘要
目的探讨血液高凝状态肺癌患者PICC置管前后抗凝治疗预防静脉血栓形成的效果。方法将2014年5月至2015年7月初次PICC置管的血液高凝状态肺癌患者30例设为对照组，将2015年8月至2016年12月初次PICC置管的血液高凝状态肺癌患者30例设为观察组。对照组在PICC置管期间按常规方法预防静脉血栓发生，观察组在常规预防的基础上增加置管前后抗凝治疗，比较2组患者静脉血栓发生率和PICC留置时间。结果观察组与对照组患者血栓发生率分别为0和20％，2组比较差异有统计学意义（P=0．024）；观察组与对照组PICC留置时间分别为95．5（21．00，117．25）d和108（97．000，130．25）d，2组比较差异有统计学意义（Z=-2．249，P=0．025）。结论血液高凝状态肺癌患者在PICC置管前后抗凝治疗可显著改善其血液高凝状态，有效预防静脉血栓形成，并能延长PICC留置时间。
Objective To explorethe efficacy of anticoagulation therapy with peripherally inserted central venous catheter （PICC） for prevention of venous thrombosis in patients with lung cancer with hypercoagulability. Methods During the period from August 2015 to December 2016, 30 patients in our hospital were enrolled as the observation group, and 30 patients from May 2014 to July 2015, with lung cancer treated with PICC catheter in our hospital were selected as the control group. In the control group, PICC during intubation by conventional methods to prevent the occurrence of venous thrombosis; while in the observation group with the additional treatment before and after anticoagulant therapy catheter based on routine prevention. Venous thrombosis incidence and the indwelling time of PICC were compared between two groups. Results The incidence of thrombosis in observation and control groups was 0 and 20% respectively, with significant difference between the two groups （P = 0.024）. The PICC retention time in observation group and control group was 95.5 （21.00, 117.25） days and 108 （97.00,130.25） days, the difference between the two groups was statistically significant （Z =- 2.249, P = 0.025）. Conclusions Anticoagulation treatment with PICC catheter before and after in hypercoagulability lung cancer patients can significantly improve the hypercoagulable state of patients, effectively prevent venous thrombosis, and prolong the PICC retention time.
作者
林小平
谌永毅
王黎黎
夏琼
李旭英
Lin Xiaoping;Chen Yongyi;Wang Lili;Xia Qiong;Li Xuying(Nursing Department, Hunan Cancer Hospital, Changsha 410013, China)
出处
《中国实用护理杂志》
2018年第12期908-911,共4页
Chinese Journal of Practical Nursing
关键词
导管插入术
中心静脉
血液高凝
肺癌
抗凝治疗
血栓
Catheterization, central venous
Hypercoagulability
Lung cancer
Anticoagulant treatment
Thrombosis
