摘要
目的探讨肥胖对支气管哮喘非急性发作期患者肺功能的影响。方法选取2015年6月至2016年2月期间我院门诊就诊的支气管哮喘非急性发作期患者120例为研究对象,依据体质指数(BMI)分为肥胖组(BMI>25kg/m^2)(n=40)和非肥胖组(≤25kg/m^2)(n=60),统计两组近6个月内症状、用药情况等,采用肺功能仪检测两组肺功能指标,包括用力肺活量(FVC)与其占预计值百分比(FVC%pred)、第1s用力呼气容积(FEV_1)与其占预计值百分比(FEV 1%pred)及FEV_1/FVC。结果肥胖组近6个月内哮喘天数、咳嗽天数显著较对照组多,口服激素或吸人激素总量显著较对照组高(P<0.01)。肥胖组FVC%pred、FEV 1%pred、FEV_1/FVC均明显低于非肥胖组(P<0.02)。结论肥胖与正常支气管哮喘非急性发作期患者相比临床哮喘、咳嗽症状更严重,用药量更大,且肺功能明显较差。
Objective To study the effect of obesity on pulmonary function in patients with bronchial asthma in non-acute episode.Methods From Jun.2015 to Feb.2016,a total of 120 patients with bronchial asthma in non-acute episode in our hospital were taken as the clinical research objects,and they were divided into obesity group（BMI25 kg/m^2）（n=40）and non-obesity group（≤25 kg/m^2）（n=60） according to body mass index（BMI）.In the past 6 months,the symptoms and drug use in the two groups were observed and compared,pulmonary function indexes including forced vital capacity（FVC）,forced vital capacity percentage of predicted value（FVC% pred）,forced expiratory volume in 1s（FEV1）,forced expiratory volume in 1 s percentage of predicted value（FEV 1% pred） and FEV1/FVCin the two groups were detected by pulmonary function instrument.Results In the past 6 months,the asthma and cough time in the obesity group was obviously less than that in the control group（P〈0.01）,the using dosage of hormone in the obesity group was obviously higher than that in the control group（P〈0.01）,the FVC% pred,FEV 1% pred and FEV1/FVC in the obesity group were all significantly lower than those in the non-obesity group（P〈0.02）.Conclusion Compared with non-obese patients,obese patients with bronchial asthma in non-acute episode has the following characteristics：more serious asthma and cough symptoms,more using dosage of drugs and obviously poorer pulmonary function.
作者
刘云阁
LIU Yun-ge.(Department of Respiratory Medicine, Baiyun District First People＇s Hospital, Guangzhou 510410, Guangdong Province, China)
出处
《罕少疾病杂志》
2017年第6期6-8,共3页
Journal of Rare and Uncommon Diseases
关键词
支气管哮喘
非急性发作期
肥胖
肺功能
Bronchial Asthma
Non-acute Episode
Obesity
Pulmonary Function
