摘要
肌动蛋白相关蛋白2/3(actin related protein 2/3,ARP2/3)复合体参与肌动蛋白的核聚与解聚,影响细胞运动能力,在形成细胞骨架和癌细胞侵袭性伪足等过程中起着重要作用。最近的研究发现ARP2/3复合体在多种肿瘤中表达异常,并与肿瘤的发展、侵袭、转移、预后密切相关。
Actin related protein 2/3（ARP2/3） complex is involved in the actin nuclear disaggregation and disaggregation, affecting cell motility. It plays an important role in the formation of cytoskeleton and invasiveness of cancer cells Pseudo-foot process. Recent studies found that ARP2/3 complex abnormally expressed in a variety of tumors, and are closely related with tumor development, invasion, metastasis, prognosis.
作者
瞿根义
QU Genyi(Department of Urology, Zhuzhou Central Hospital, Zhuzhou Hunan 412007, Chin)
出处
《临床与病理杂志》
2018年第2期412-417,共6页
Journal of Clinical and Pathological Research
