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前列腺癌骨转移的破坏病理机制及治疗方案 被引量:2

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摘要 与其他实体肿瘤相比,前列腺癌的远处转移具有明显的嗜骨性转移特征,骨为其最常见的远处转移部位[1]。和其他组织相比,前列腺癌对骨髓组织的亲和力更强,可引起成骨细胞的损伤和增生活跃。有关报道资料显示,大概有七成前列腺癌患者在癌症常态发展的过程中会产生骨转移病症[2]。前列腺癌骨转移可引起病理性骨折、脊髓压迫及恶性高钙血症等并发症,称为骨相关事件(SRE)[3],本文就近年来前列腺癌骨破坏病理机制及治疗研究进展情况进行综述。
出处 《中国老年学杂志》 CAS 北大核心 2018年第7期1770-1773,共4页 Chinese Journal of Gerontology
基金 国家自然科学基金(81502220) 天津市应用基础与前沿技术研究计划重点项目(15JCZDJC35900)
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