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慢性非特异性炎症在多囊卵巢综合征发病作用中的研究进展 被引量:16

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摘要 多囊卵巢综合征病因尚不明确。近年来有证据表明,多囊卵巢综合征患者体内存在慢性非特异性炎症状态,可能是其发病原因之一。过量的脂肪组织、氧化应激反应、NF-κB途径激活等均可造成慢性非特异性炎症状态,而这种炎症状态引起的机体高炎症因子水平会影响卵泡发育、导致排卵障碍、引起高雄激素血症、胰岛素抵抗,最终形成以不孕为主要表现的多囊卵巢综合征,亦可加速2型糖尿病、心血管疾病、代谢综合征等PCOS远期并发症的进展。本文将介绍慢性非特异性炎症对多囊卵巢综合征发病机制及其远期并发症的影响。
作者 孙迪 李蓉
出处 《中国妇产科临床杂志》 CSCD 北大核心 2018年第2期180-181,共2页 Chinese Journal of Clinical Obstetrics and Gynecology
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