摘要
目的了解神经系统副肿瘤综合征(PNS)的临床特点。方法回顾分析36例神经系统副肿瘤综合征患者的临床资料进行总结。结果 36例神经系统副肿瘤综合征平均年龄69.5岁,男女比例为1∶0.714,神经系统表现为边缘叶脑炎、亚急性小脑变性、脑干脑炎、周围神经病、Lambert-Eaton肌无力综合征,肿瘤来源以肺癌为主,占80.56%。75%的病例先于肿瘤表现出PNS的症状。结论 PNS表现多种多样,早期识别症状对于诊治PNS发现肿瘤是非常重要的。
Objective To investigate the clinical characteristics of paraneoplastis neurological syndrome（PNS）. Methods The clinical data of 36 cases with PNS were analyzed retrospectively. Result The average age of 36 patients with PNS was 69.5 years. And the ratio of male to female was 1： 0. 714. The neurological manifestations included limbic encephalitis, subacute cerebellar degeneration, brainstem encephalitis, peripheral neuropathy, Lambert-Eaton myasthenia syndrome. Lung cancer was the major origin of PNS for the percentage of 80. 56 % in all original tumors. The symptoms of PNS were found before the tumors in 75% cases. Conclusions The manifestations of PNS are various. Early identification of symptoms is important for the diagnosis and treatment of PNS.
作者
曾倩
曾昭祥
ZENG Qian , ZENG Zhao-xiang(Department of Internal Neurology, the People＇Hospital of Inner Mongolia Autonomous Region, Huhhot, Inner Mongolia, 010017, Chin)
出处
《中国冶金工业医学杂志》
2018年第2期132-133,共2页
Chinese Medical Journal of Metallurgical industry
关键词
副肿瘤综合征
神经系统
自身免疫
Paroneoplastic neurological syndrome
Nervous system
Autoimmune
