摘要
对老年５０例心脑血管病、３２例糖尿病病人及４５例健康老年人进行ＯＧＴＴ及ＩＲＴ并予以分析，结果空腹及餐后胰岛素释放水平于老年心脑血管病组与糖尿病组较健康老人组升高，餐后１２０ｍｉｎ及１８０ｍｉｎ尤为明显，同步测定血糖无相应降低；胰岛素敏感性测定Ｇ／Ｉ、胰岛素峰值／基础值、胰岛素△峰值与ＡＧ／ＡＩ对糖尿病无临床意义甚至导致误解。仅ＩＡＩ数值于心脑血管病组及糖尿病组均明显降低，表明胰岛素抵抗（ＩＳＲ）存在。ＩＡＩ是一项敏感性强、适用各种病情的ＩＳＲ指标。
The results of OGTT and plasma insulin releasing test (IRT) in 82 old aged patients with cardio cerebrovascular disease and diabetes mellitus (NIDDM) and 45 old healthy subjects (OHS) were analysed.It showed that fasting and post meal plasma insulin levels were higher in cardio cerebrovascular disease and NIDDM than those in OHS,especially at two and three hours after meal,but without lowering of plasma glucose levels.Insulin sensitive index (ISI),G/I,peak value/basic value,insulin △ peak value and AG/AI had no clinical significance,but would even cause misreading in NIDDM.IAI reduced prominently in both cardio cerebrovascular disease and NIDDM,indicating the presence of insulin resistance (ISR).It is suggested that there is a common base for the pathogenesis of the above mentioned geriatic diseases,ie.ISR.IAI is a highly sensitive ISR index available for any condition.
出处
《南昌大学学报（医学版）》
CAS
1996年第4X期50-53,共4页
Journal of Nanchang University：Medical Sciences
