摘要
目的对右美托咪定联合舒芬太尼在全麻患者术后镇痛中的应用效果进行观察。方法选取2016年9月~2017年8月我院收治的104例全麻手术患者作为研究对象,按照随机数字表法将其分为研究组和对比组,每组各52例。对比组患者使用舒芬太尼进行镇痛,研究组患者使用右美托咪定联合舒芬太尼进行镇痛。对比分析两组患者的Ramsay镇静评分、VAS评分、切口疼痛面积及不良反应发生率。结果两组患者各时间段的Ramsay镇静评分比较,差异无统计学意义(P>0.05)。术后30 min、3 h、48 h,研究组患者的VAS评分均低于对比组,差异有统计学意义(P<0.05)。术后30 min、3 h、48 h,研究组患者的术后切口疼痛面积均小于对比组,差异有统计学意义(P<0.05)。研究组患者的不良反应发生率为7.69%,对比组患者的不良反应发生率为11.53%。两组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。结论全麻患者术后镇痛中使用右美托咪定联合舒芬太尼的效果更好,起到有效减轻疼痛评分、较小切口疼痛面积效果,应在临床实践中予以广泛推广并使用。
Objective To observe the application effect of Dexmedetomidine combined with Sufentanil for postoperative analgesia in general anesthesia patients.Methods A total of 104 patients undergoing general anesthesia in our hospital from September 2016 to August 2017 were selected as subjects.According to a random number table method,they were divided into study group and control group,52 cases in each group.In the control group,Sufentanil was used for analgesia,while in the study group,Dexmedetomidine combined with Sufentanil for analgesia was adopted.The Ramsay sedation score,visual analogue scale （VAS） score,incision pain area and incidence of adverse reactions were compared and analyzed in the two groups.Results There was no statistically significant difference in Ramsay sedation score between the two groups （P〉0.05）.After 30 min,3 h and 48 h,the VAS score of the study group was lower than that of the control group, and the differences were statistically significant （P〈0.05）.After 30 rain,3 h and 48 h,the pain area of the postoperative incision in the study group was smaller than that in the control group,and the differences were statistically significant （P〈0.05）.The incidence of adverse reactions in the study group was 7.69%,while it was 11.53% in the comparison group,there was no significant difference in the incidence of adverse reactions between the two groups （P〉0.05）.Conclusion The effect of Dexmedetomidine combined with Sufentanil for postoperative analgesia in general anesthesia patient is better compared with sole Sufentanil,which can effectively relieve pain and reduce the area of incision pain,and should be widely used and promoted in clinical practice.
出处
《中国当代医药》
2018年第6期68-70,共3页
China Modern Medicine
关键词
右美托咪定
舒芬太尼
全麻患者
术后镇痛
Dexmedetomidine
Sufentanil
General anesthesia patients
Postoperative analgesia
