摘要
表型组学是一门在基因组水平上系统研究某一生物或细胞在各种不同环境条件下所有表型的学科。识"态"和调"态"是中医学认识和治疗疾病的一个重要思维和手段。中医学从临床表现到"态"归纳的思维和理念,与表型组学的研究理念具有一定的共通性。中医学朴素的调"态"整体观为表型组学在基因水平上理解人类疾病多样性提供参考;而利用表型组学、系统生物学等研究方法,可以为揭示中医学"态"的本质和"调态"机制提供助力,增强中医治疗的精准性和科学性。
Phenotypics is a subject that systematically studies all phenotypes of a living organism or cell in a variety of different environmental conditions at the genomic level. Identifying and adjusting the balance of the body is an unique understanding of traditional Chinese medicine(TOM) and treatment of disease. TCM has a high degree of commonality with phenomics in the process of understanding of the disease. The simple holistic view of TCM provides a reference for the understanding of the diversity of hu- man diseases at the genetic level of phenotypics. Using the method of phenotypic and systematic biology research, will help to reveal the essence of syndrome and TCM treatment mechanism, and will promote the accuracy and the scientific nature of TCM treatment.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2018年第3期368-370,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家自然科学基金重点资助项目(No.81430097)
关键词
表型组学
中医学
调态理念
精准医学
phenomics
traditional Chinese medicine
the concept of identifying and adjusting the balance of the body
precision medicine