摘要
目前研究认为,肥胖是乳腺癌的预后不良因素之一,肥胖可能增加女性乳腺癌的发病率和病死率,降低乳腺癌手术、化疗及放疗的治疗效果。减重干预是减轻体重、改善肥胖的有效途径。近年来,研究发现减重有助于延缓肥胖小鼠乳腺癌的进展与转移,可能降低肥胖者乳腺癌的发病率与病死率,调节肥胖乳腺癌患者的血清标志物水平,并对肥胖乳腺癌患者的生命质量、饮食行为、生活方式等产生积极影响。减重干预有望成为肥胖的乳腺癌长期存活者的重要辅助治疗手段。
According to current studies,obesity is a well-established risk factor for poor prognosis in women with breast cancer,which can increase the risk of female breast cancer morbidity and mortality,reduce the effectiveness of surgery,chemotherapy and radiotherapy.The effective way to treat obesity is weight loss intervention.Weight loss intervention contributes to reverse breast cancer progression and metastasis in mice,reduce breast cancer morbidity and mortality in obese women,adjust the level of serum markers in breast cancer patients,and have a positive effect on the quality of life,dietary behavior and lifestyle for obese breast cancer patients.It is expected to be an important auxiliary therapy of breast carcinoma survivors with obesity.
出处
《医学与哲学（B）》
2018年第2期53-57,68,共6页
Medicine & Philosophy(B)
基金
2017年云南省科技厅-昆明医科大学应用基础研究联合专项(2017FE468)
关键词
乳腺癌
减重干预
肥胖
营养
breast cancer
weight loss intervention
obesity
nutrition
