摘要
探讨高血压合并急性心肌梗死患者的血压变异性对冠脉病变程度及近期预后的影响。选择2016年8月~2017年8月在郑州大学第一附属医院住院的高血压合并急性心肌梗死患者103例,基于患者冠脉造影结果进行Gensini评分,其中52例为轻度病变组(<50分),51例为重度病变组(≥50分),比较两组各临床指标及血压变异性,比较两组入院30天内心血管不良事件(死亡、心力衰竭、心肌梗死后心绞痛、严重心律失常)的发生率,分析心血管不良事件的危险因素。重度病变组的全天收缩压变异性、全天舒张压变异性、白天收缩压变异性、白天舒张压变异性、夜间收缩压变异性、夜间舒张压变异性水平均高于轻度病变组,其中全天收缩压变异性、全天舒张压变异性、白天收缩压变异性差异有统计学意义(P<0.05)。全天收缩压变异性、全天舒张压变异性、白天收缩压变异性升高导致心血管不良事件发生的风险增加(P<0.05)。因此,在高血压合并急性心肌梗死患者中,血压变异性与冠脉病变程度相关,降压时兼顾降低血压变异性,可能有效减少心血管不良事件的发生。
The paper is to investigate the relationship between blood pressure variability and severity of Coronary artery lesion in the patients with hypertension and Acute myocardial infarction.The paper also analyses the impact of blood pressure variability on the short term prognosis.The present study included 103 hypertension patients with acute myocardial infarction from August 2016 to August 2017 in the First Affiliated Hospital of Zhengzhou University.We evaluated Gensini score of 103 hypertension patients with acute myocardial infarction.We classified them as mild lesion group(score<50,n=52)and severe lesion group(score≥50,n=51).All the clinical index and blood pressure variability were compared of two groups to find out differences.The authors examine the risk factors of cardiovascular adverse events.All day systolic blood pressure variability,all day diastolic blood pressure variability,daytime systolic blood pressure variability,daytime diastolic blood pressure variability,nighttime systolic blood pressure variability and nighttime diastolic blood pressure variability levels in severe lesion group were higher than the mild lesion group.There were only statistical differences in the all day systolic blood pressure variability,all day diastolic blood pressure variability and daytime systolic blood pressure variability between two group(P<0.05).All day systolic blood pressure variability,all day diastolic blood pressure variability and daytime systolic blood pressure variability increase the risk of adverse cardiovascular events(P<0.05).Blood pressure variability is correlated with the degree of coronary artery lesion in patients with hypertension complicated with acute myocardial infarction.Reducing blood pressure variability during hypertension treatment may effectively reduce the incidence of adverse cardiovascular events.
出处
《医学与哲学（B）》
2018年第2期37-39,93,共4页
Medicine & Philosophy(B)
关键词
急性心肌梗死
冠脉病变程度
血压变异性
近期预后
acute myocardial infarction
serverity of coronary artery lesion
blood pressure variability
shortterm prognosis
