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消溶稳斑方对冠心病患者颈总动脉粥样硬化斑块的作用及炎性因子的影响 被引量:2

Effect of dissolving Wenban recipe on common carotid artery atherosclerotic plaque in patients with coronary heart disease and the role of inflammatory factors
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摘要 目的:观察消溶稳斑方对冠心病不稳定性心绞痛患者颈总动脉粥样硬化斑块的作用及炎性因子的影响。方法:收治冠心病不稳定性心绞痛患者60例,随机分两组。对照组接受基础治疗,观察组在此基础上加用消溶稳斑方,治疗前及治疗后对两组患者的颈总动脉粥样硬化斑块及外周血清炎性因子进行测量,且在治疗后对两组患者的临床疗效进行评价。结果:临床总有效率治疗组显著高于对照组(P<0.05);观察组患者治疗后的IMT和斑块面积均显著优于对照组(P<0.01);治疗后观察组患者hSCRP和IL-10水平显著低于对照组(P<0.01)。结论:消溶稳斑方对冠心病不稳定性心绞痛具有显著疗效,并能降低炎性因子水平,对改善动脉粥样硬化斑块有明显的作用。 Objective:To observe the effect of dissolving Wenban recipe on common carotid artery atherosclerotic plaque in patients with coronary heart disease and the role of inflammatory factors.Methods:60 patients with coronary heart disease with unstable angina pectoris were selected,they were randomly divided into the two groups,the control group received basic treatment,while on this basis,the observation group was treated with dissolving Wenban recipe.We measured common carotid artery atherosclerotic plaque and peripheral serum inflammatory factors in the two groups of patients before and after treatment,and after treatment,the clinical efficacy of the two groups of patients was evaluated.Results:The clinical total effective rate of the treatment group was significantly higher than that of the control group(P〈0.05).After treatment,the area of IMT and plaque in the observation group was significantly lower than that of the control group(P〈0.01).After treatment,the level of hSCRP and IL-10 in the observation group was significantly lower than that of the control group(P〈0.01).Conclusion:The dissolving Wenban recipe has obvious curative effect on unstable angina pectoris of coronary heart disease,and can decrease the level of inflammatory factors,and has obvious effect on improving atherosclerosis.
作者 邵静 杨莉霞
出处 《中国社区医师》 2018年第8期111-112,114,共3页 Chinese Community Doctors
关键词 消溶稳斑方 不稳定心绞痛(UAP) 动脉粥样硬化(AS) 炎性因子 Dissolving Wenban recipe Unstable angina pectoris(UAP) Atherosclerosis(AS) Inflammatory factors
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