期刊文献+

泼尼松联合沙利度胺治疗重度Ⅱ型麻风反应疗效评价 被引量:7

Assessment of the efficacy of prednisone combined with thalidomide in the treatment of severe type-2 leprosy reactions
下载PDF
导出
摘要 目的:评价泼尼松联合沙利度胺治疗重度Ⅱ型麻风反应患者的疗效。方法:重度Ⅱ型麻风反应患者38例给予泼尼松30 mg/d早晨顿服同时给予沙利度胺100 mg/次,每日3次,待症状控制后逐渐减量至停药,总疗程4个月。结果:重度Ⅱ型麻风反应患者痊愈率86.84%、显效率94.73%。结论:泼尼松联合沙利度胺治疗重度Ⅱ型麻风反应患者疗效显著。 Objective: To assess the efficacy of prednisone combined with thalidomide in the treatment of severe type-2 leprosy reactions. Methods: Thirty patients with severe type-2 leprosy reaction were treated with prednisone,30 mg,once a day,and thalidomide,100 mg,three times a day. The drug was gradually reduced after symptoms were controlled,The total course was 4 months. Results: The recovery rate and effect rate were 86.84% and 94.73%. Conclusion: Prednisone combined with thalidomide is effective in the treatment of severe type-2 leprosy reaction.
作者 卢海洪
出处 《中国麻风皮肤病杂志》 2018年第2期77-79,共3页 China Journal of Leprosy and Skin Diseases
关键词 重度Ⅱ型麻风反应 沙利度胺 泼尼松 severe II leprosy reaction thalidomide prednisone
  • 相关文献

参考文献6

二级参考文献64

  • 1王景权,张壤之,皋官蔚.两种治疗方法与麻风神经损害相关性研究[J].临床皮肤科杂志,1996,25(3):150-151. 被引量:1
  • 2Kumar B,Dogra S,Kaur I.Epidemiological characteristics of leprosy reactions:1 5 years experience from North India.Int J Lepr Other Mycobact Dis 2004;72:125-133. 被引量:1
  • 3Pocaterra L,Jain S,Reddy R,et al.Clinical course of erythema nodosum leprosum:an 11-year cohort study in Hyderabad,India.Trop Med Hyg 2006;74:868-879. 被引量:1
  • 4Moher D,Cook DJ,Eastwood S,et al.Improving the quality of reports of meta-analyses of randomised controlled trials:the QUOROM statement.Quality of Reporting of Meta-analyses.Lancet 1999;354:1896-1900. 被引量:1
  • 5Moher D,Schulz KF,Altman DG,et al.The CONSORT statement:revised recommendations for improving the quality of reports of parallel-group randomized trials.JAMA 2001;285:1987-1991. 被引量:1
  • 6Jadad AR,Moore RA,Carroll D,et al.Assessing the quality of reports of randomized clinical trials:is blinding necessary? Control Clin Trials 1996;17:1-12. 被引量:1
  • 7Kaur I,Dogra S,Narang T,et al.Comparative efficacy of thalidomide and prednisolone in the treatment of moderate to severe erythema nodosum leprosum:a randomized study.Australas J Dermatol 2009;50:181-185. 被引量:1
  • 8Sales AM,de Matos HJ,Nery JA,et al.Double-blind trial of the efficacy of pentoxifylline vs thalidomide for the treatment of type II reaction in leprosy.Braz J Med Biol Res 2007;40:243-248. 被引量:1
  • 9Villahermosa LG,Fajardo TT Jr,Abalos RM,et al.A randomized,double-blind,double-dummy,controlled dose comparison of thalidomide for treatment of erythema nodosum leprosum.Am J Trop Med Hyg 2005;72:518-526. 被引量:1
  • 10Girdhar A,Chakma JK,Girdhar BK.Pulsed corticosteroid therapy in patients with chronic recurrent ENL:a pilot study.Indian J Lepr 2002;74:233-236. 被引量:1

共引文献11

同被引文献29

引证文献7

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部