摘要
目的探讨N-甲基-D-天冬氨酸受体抗体(NMDA)介导的自身免疫性脑炎的临床、辅助检查特点、治疗方案。方法分析2014年6月-2017年4月内在新疆维吾尔自治区人民院儿科住院治疗并明确诊断为7例抗NMDA受体脑炎患者的临床特点、辅助检查,总结对不同治疗方案和预后的关系。结果 7例患儿临床主要表现为显著的肢体运动不协调、精神症状、癫痫,头颅MRI未见异常信号,脑电图可见异常脑电波,脑脊液NMDA抗体受体阳性,其中1例放弃治疗未能随访外,其余6例预后良好。结论儿童NMDA受体脑炎早期识别、及早诊断、及时选择合适的治疗有助于该病的预后。
Objective To summarize the clinical manifestations, immunotherapeautic response and how to choose the oppropriate therapeutic schedule. Methods The clinical features, blood/cerebrospinal fluid markers, and the progress of different treatment were observed. Results 7 patients with different significant movement disorders, psychiatric symtoms, epilepsy. All electroencephalographs showed slow wave activity without epileptic from discharges. Conclusions Early recognition and early diagnosis and timely appropriate treatment is helpful for the prognosis of the disease.
出处
《新疆医学》
2017年第12期1432-1434,共3页
Xinjiang Medical Journal
