摘要
目的 探讨右美托咪定联合阴茎背神经阻滞麻醉应用在小儿包皮环切手术中的镇痛效果及安全性.方法 选取包皮环切手术治疗的患儿130例,采用随机数字表法分为观察组和对照组,每组65例.对照组采用全凭吸入七氟烷麻醉,观察组采取右美托咪定联合阴茎背神经阻滞麻醉,对比两组麻醉效果及安全性.结果 观察组诱导后平均动脉压[（69.89±5.24）mmHg]、苏醒时平均动脉压[（70.14±5.30）mmHg]、诱导后心率[（100.36±10.67）次/min]、苏醒时心率[（102.64±10.58）次/min]、诱导后血氧饱和度[（98.25±0.63）％]、苏醒时血氧饱和度[（98.64±0.66）％]等生命体征各项指标与对照组比较差异均无统计学意义（t=0.130、0.215、0.548、0.613、0.106、0.257,均P〉0.05）.观察组睫毛反射消失时间为（23.16±2.13）s,手术时间为（9.70±1.24）min,苏醒时间为（10.03±1.27）min;对照组睫毛反射消失时间为（27.98±3.87）s,手术时间为（11.88±2.87）min,苏醒时间为（11.89±3.87）min,差异均有统计学意义（t=8.797、5.621、6.633,均P〈0.05）.观察组术后躁动评分为（2.75±1.25）分,镇静评分为（1.97±0.38）分,疼痛评分为（5.26±1.44）分;对照组术后躁动评分为（6.78±2.89）分,镇静评分为（1.11±0.13）分,疼痛评分为（8.97±3.64）分,差异均有统计学意义（t=10.318、17.236、7.641,均P〈0.05）.结论 右美托咪定联合阴茎背神经阻滞麻醉应用在小儿包皮环切手术中起效快,患儿生命体征稳定,术后躁动少,值得在临床上推广应用.
Objective To investigate the effect and safety of dexmedetomidine combined with dorsal penile nerve block for circumcision in children .Methods 130 children with circumcision were divided into the observation group and the control group according to the digital table ,65 cases in each group .The control group received total inhalation of seven halothane anesthesia ,and the observation group received dexmedetomidine combined with dorsal penile nerve block anesthesia .The efficacy and safety of the two groups were compared .Results In the observation group after induction,the mean arterial pressure[（69.89 ±5.24）mmHg],awake and mean arterial pressure[（70.14 ± 5.30）mmHg],rhythm of the heart after induction [（100.36 ±10.67）times/min],the rhythm of the heart when they woke up[（102.64 ±10.58） times/min],blood oxygen saturation after induction [（98.25 ±0.63）%],awake and blood oxygen saturation[（98.64 ±0.66）%]and other signs of vital signs had no statistically significant differences compared with the control group （F=0.130,0.215,0.548,0.613,0.106,0.257,all P〉0.05）.In the observation group,the eyelash reflex disappearing time , operation time, awakening time were （ 23.16 ±2.13 ） s, （ 9.70 ± 1.24）min,（10.03 ±1.27）min,respectively,which in the control group were（27.98 ±3.87）s,（11.88 ±2.87）min, （11.89 ±3.87） min,respectively,there were statistically significant differences between the two groups （ t=8.797, 5.621,6.633,all P〈0.05）.In the observation group,the postoperative agitation score ,sedation score,pain score were（2.75 ±1.25）points,（1.11 ±0.13）points,（5.26 ±1.44）points,respectively,which in the control group were （6.78 ±2.89） points,（1.11 ±0.13） points,（8.97 ±3.64） points,respectively,there were statistically significant differences between the two groups （t =10.318,17.236,10.318,all P 〈0.05）.Conclusion Application of dexmedetomidine combined with penile dorsal nerve block anesthesia in pediatric circumcisio
出处
《中国基层医药》
CAS
2018年第2期147-150,共4页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省温州市公益性科技计划项目（Y20160385）
