摘要
目的:分析中药封包联合西药对慢性心力衰竭(chronic heart failure,CHF)患者心功能及生活质量的影响。方法:选取CHF患者作为研究对象,随机分为对照组及观察组,对照组给予常规西药治疗,观察组给予中药封包联合西药治疗,比较两组患者治疗前后心功能及生存质量调查表得分的差异。结果:治疗前,观察组和对照组LVEDD、LVESD、LVEF及血清BNP无明显差异(P〉0.05),两组治疗前后上述4项指标组内比较均有统计学差异(P〈0.05),治疗后两组间比较,观察组LVEF明显高于对照组,血清BNP明显低于对照组(P〈0.05),而LVEDD及LVESD两组间无差异(P〉0.05);治疗前,观察组和对照组生存质量量表各维度无明显差异(P〉0.05),两组治疗前后上述各维度组内比较均有统计学差异(P〈0.05),治疗后两组间比较,观察组身体、情绪及综合领域得分明显低于对照组(P〈0.05),而其他领域得分两组间无差异(P〉0.05)。结论:中药封包与西药联合应用,可以进一步提高心脏射血分数,降低血清BNP水平,改善心功能,提高患者的生存质量,值得进一步推广应用。
Objective: To analyze the effect of traditional Chinese medicine combined with western medicine on cardiac function and quality of life in patients with chronic heart failure( CHF). Methods: The patients with CHF in our hospital were collected and randomly divided into the control group and the observation group. The patients in the control group were given routine medicine treatment and the observation group was given traditional Chinese medicien combined with western medicine. The difference on the heart function and the scores of quality of life were compared between the two groups. Results: The LVEDD,LVESD,LVEF and BNP had no significant difference between two groups before treatment( P 0. 05),and the differece was statistically significant before and after treatment( P 0. 05). After treatment,the LVEFin the observation group was significantly higher and the BNP was lower than those of the control group( P 0. 05),but the LVEDD and LVESDhad no significant difference between the two groups( P 0. 05). The scores of quality of life were not significant between two groups before treatment( P 0. 05),and the differece was statistically significant before and after treatment( P 0. 05). After treatment,the scores of body,emotion and comprehensive field in the observation group were significantly lower than those of the control group( P 0. 05),but the scores of other domain were not significant between the two groups( P 0. 05). Conclusion: The combination of traditional Chinese and western medicine can further improve the LVEF and decrease the level of the BNP,improve heart functionand the quality of life,and is worthy of further promotion.
出处
《中华中医药学刊》
CAS
北大核心
2018年第3期729-731,共3页
Chinese Archives of Traditional Chinese Medicine
基金
广东省中医药局科研项目(20171285)
关键词
中药
慢性心力衰竭
心脏功能
生存质量
traditional Chinese medicine
chronic heart failure
cardiac function
quality of life