摘要
目的：探讨益气活血通络汤联合神经节苷脂对外伤性颅脑出血患者血清超氧化物歧化酶（SOD）、D-二聚体（D-D）、C-反应蛋白（CRP）及预后的影响。方法：将130例外伤性颅脑出血患者按照数字表法随机分为两组。对照组65例给予神经节苷脂治疗,试验组65例在对照组基础加用益气活血通络汤。比较两组临床预后、格拉斯哥昏迷（GCS）评分及SOD、D-D、CRP的差异。结果：试验组患者治愈率、总有效率分别为64.6%、95.4%高于对照组36.9%、76.9%（P〈0.05）;治疗4周后、治疗8周后试验组GCS评分升高,也高于同期对照组,呈逐渐升高趋势（P〈0.05）;治疗4周后、治疗8周后试验组D-D、CRP水平降低,也低于同期对照组,呈逐渐降低趋势（P〈0.05）;治疗4周后、治疗8周后试验组SOD水平升高,也高于同期对照组,呈逐渐升高趋势（P〈0.05）。结论：益气活血通络汤联合神经节苷脂对外伤性颅脑出血患者效果佳,其可有效降低D-D、CRP水平,升高SOD水平,改善患者临床症状,临床有效率也较高,值得临床选择。
Objective：To explore the effects of Yiqi Huoxue Tongluo Decoction combined with ganglioside on serum superoxide dismutase（SOD）,D-dimer（DD）,C-reactive protein（CRP）and prognosis in patients with traumatic brain hemorrhage.Methods：130 cases of traumatic brain hemorrhage in our hospital were randomly divided into two groups according to the digital table method.In the control group,65 cases were treated with ganglioside,65 cases in the experimental group were treated with Yiqi Huoxue Tongluo Decoction.Comparison of the two groups of clinical efficacy,Glasgow coma（GCS）score and SOD,D-D,CRP differences.Results：The cure rate and total effective rate were 64.6% and 95.4% in the experimental group,and were higher than the control group 36.9% and 76.9%,respectively,comparison was statistically significant（P0.05）.After 4 weeks and 8 weeks of treatment,the GCS score of the experimental group increased,and was higher than that of the control group,was gradually increased trend,comparison was statistically significant（P0.05）.After 4 weeks and 8 weeks of treatment,the levels of D-D and CRP in the experimental group were decreased,and was lower than that of the control group,was gradually decreased trend,comparison was statistically significant（P0.05）.After 4 weeks and 8 weeks of treatment,the levels of SOD in the experimental group was increased,and was higher than that of the control group,was gradually increased trend,comparison was statistically significant（P0.05）.Conclusion：Yiqi Huoxue Tongluo Decoction combined with ganglioside on traumatic brain hemorrhage in patients with good results,which can effectively reduce the DD,CRP levels,increased SOD levels,improve clinical symptoms,clinical efficacy is also high,and is worthy of clinical choice.
出处
《辽宁中医药大学学报》
CAS
2018年第2期124-126,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
湖南省教育厅科研基金项目(14B132)
