摘要
Caspase-3作为凋亡执行和效应过程中的关键酶,其级联活化反应是导致细胞发生凋亡的重要途径。肿瘤的形成是细胞增殖和凋亡失衡的结果,有关Caspase-3与头颈肿瘤的研究近年来也备受关注,本文围绕Caspase-3在头颈肿瘤的作用及其相关机制进行综述。
The imbalance of cell proliferation and apoptosisplays a great role in the development of Tumor. Caspase associated cascade reaction is the important pathway for apoptosis.Caspase-3 is the key protease in theprocess of apoptosis. Therefore, Research on relationship between Caspase-3 and head and neck tumors has attracted much attention recently. In this paper, the role of Caspase-3 in head and neck cancer and its related mechanisms were reviewed.
出处
《中国医学文摘(耳鼻咽喉科学)》
2018年第1期98-101,共4页
Chinese Medical Digest(Otorhinolaryngology)
基金
重庆市卫计委科研基金资助项目(2016MSXM127)
关键词
凋亡
程序性坏死
头颈部肿瘤
(Apoptosis)
(Necroptosis)
(Head andNeckTumors)