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反流性疾病与儿童慢性咳嗽

Reflux diseases and chronic cough in children
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摘要 慢性咳嗽是儿童常见的临床症状。反流性疾病包括胃食管反流性疾病(gastroesophageal reflux disease,GERD)及咽喉反流性疾病(laryngopharyngeal reflux disease,LPRD),被认为是导致儿童慢性咳嗽的原因之一。相较于酸性反流,非酸性反流可能是GERD引起儿童慢性咳嗽更重要的因素。儿童慢性咳嗽患者中LPRD有很高的发病率。除对咽喉部的直接损伤和刺激外,LPRD还可能通过影响儿童喉软骨发育,诱发中耳炎、鼻窦炎而导致上气道咳嗽综合征加重儿童慢性咳嗽。 Chronic cough is a common clinical symptom in children. Reflux diseases, including gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux disease (LPRD) , are believed to be one of the most important causes of children' s chronic cough. In contrast to acidic reflux, non-acidic reflux may be more important in the cause of chronic cough. It has a high incidence of LPRD in children with chronic cough. In addition to the direct throat injury and stimulation, LPRD may also affect children's laryngeal cartilage development, inducing otitis media and sinusitis, which can lead to upper respiratory airway cough syndromemaking chronic cough worse.
作者 陆敏 尹冰如
出处 《中国医学文摘(耳鼻咽喉科学)》 2018年第1期33-35,46,共4页 Chinese Medical Digest(Otorhinolaryngology)
关键词 胃食管反流 咽喉反流 儿童 慢性咳嗽 (Gastroesophageal Reflux) (Laryngopharyngeal Reflux) (Child) (Chronic Cough)
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