摘要
目的分析国内外蛇咬伤并发破伤风感染的文献,了解蛇咬伤患者发生破伤风的情况。方法通过检索中国知网数据库、万方数据库、维普数据库和MEDLINE、Web of Science、Embase及Science Direct数据库,以中文检索词为"蛇咬伤"和"破伤风",英文检索词为"snake bite"and"tetanus",检索时间1953年1月至2017年10月。结果共检索到98篇文献,其中明确记录了蛇咬伤并发破伤风的患者资料的文献有8篇,中文文献6篇,英文文献2篇;共16例患者,其中中国11例,尼日利亚4例,泰国1例;咬伤部位均为四肢;9例患者为血循毒蛇伤,7例为混合毒蛇伤;蛇咬伤患者发生破伤风之前,1例患者注射了破伤风抗毒素,13例患者用中草药外敷伤处,2例患者未做处理;预后分析显示16例患者中12例治愈,4例死亡,其中死亡患者均有外敷草药史。结论四肢外伤、外敷草药、血循毒或者混合毒蛇咬伤的患者应加强破伤风感染的预防。
ObjectiveTo analyze the literature of snakebite and tetanus infection at home and abroad, and understand the situation of tetanus in snakebite patients.
MethodsThe retrieval of China CNKI database, Wanfang database, VIP database and MEDLINE, Web of Science Embase and Science Direct database was performed with ＂ snake bite＂ and ＂ tetanus＂ as the key words, and the retrieval time from January 1953 to October 2017.
ResultsA total of 98 articles was retrieved, which clearly records the snakebite patient data with tetanus has collected 8 literatures, Chinese 6 literatures, English 2 articles; a total of 16 patients, including 11 cases of Chinese, 4 in Nigeria, 1 in Thailand; the bite sites were limbs; 9 patients with blood circulation the snake wound, 7 cases of mixed snakebite; snake bite patients with tetanus before; 1 patients were injected with Tetanus Antitoxin, 13 patients were treated with Chinese herbal medicine on the wound, 2 patients were untreated. Prognosis analysis showed that in 16 cases, 12 cases were cured, 4 cases died, and the death of the patients had the history of herbal.
ConclusionsThe prevention of tetanus infection should be strengthened in patients with extremities trauma, external application of herbs, blood based drugs, or mixed venomous snake bites.
出处
《中国医师杂志》
CAS
2018年第2期177-179,共3页
Journal of Chinese Physician
