摘要
背景:当机体出现骨质疏松时极易发生骨折。其中髋骨骨折最为常见,进而引发股骨头坏死。手术治疗的同时进行抗骨质疏松治疗可提高股骨头坏死的总体治疗效果。目的:对髋关节置换术结合围术期抗骨质疏松治疗骨质疏松致股骨头坏死的临床疗效进行分析。方法:选择2016年1月至2017年1月于我院骨科治疗的骨质疏松性股骨头坏死患者112例,随机分为对照组和观察组,每组各56例。对照组采用髋关节置换术进行治疗,观察组采用髋关节置换术联合抗骨质疏松药物治疗。结果:观察组总有效率高于对照组(96.43%vs 82.14%,P<0.05),两组经治疗后关节功能评分、骨密度值、血清骨钙素及血小板源性生长因子均增加,且观察组上述指标水平高于对照组(P<0.05),观察组生活质量评分优于对照组(P<0.05)。结论:髋关节置换术联合围术期抗骨质疏松治疗骨质疏松致股骨头坏死具有较好临床疗效。
Background： It is prone to fracture when the body happens to be osteoporosis, and hip fracture is most common which will further lead to femoral head necrosis. Combination of surgical treatment and anti osteoporosis treatment can enhance the overall efficacy on femoral head necrosis. Objective： To analyze the clinical effect of hip arthroplasty combined with perioperative anti osteoporosis in the treatment of femoral head necrosis caused by osteoporosis. Methods： A total of112 patients with osteoporotic femoral head necrosis were randomly divided into two groups with 56 patients in each. The control group was treated by hip arthroplasty, and the observation group was treated with anti osteoporosis drug and hip arthroplasty simultaneously. Results： The total effective rate of the observation group was higher than that of the control group（96.43% vs 82.14%, P〈0.05）. Joint function score, bone mineral density, serum osteocalcin and platelet derived growth factor（PDGF） values in both groups increased after treatment, and those in the observation group were higher than those in the control group（P〈0.05）. The quality of life score in the observation group was significantly higher than that in the control group（P〈0.05）. Conclusions： Hip arthroplasty combined with perioperative anti osteoporosis in the treatment of femoral head necrosis caused by osteoporosis shows a good clinical effect.
出处
《中华骨与关节外科杂志》
2017年第5期404-407,共4页
Chinese Journal of Bone and Joint Surgery
关键词
髋关节置换术
抗骨质疏松治疗
股骨头坏死
Hip Arthroplasty
Anti-Osteoporosis Treatment
Femoral Head Necrosis
