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降压定眩片对高血压患者雌二醇水平及动态动脉硬化指数的影响

The action on dihydrotheelin estradiol and Ambulatory Arterial Stiffness Index(AASI)of jiang ya ding xuan pian on patients of essential hypertension
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摘要 目的:探讨滋水涵木法治疗阴虚阳亢型原发性高血压的临床疗效。方法:选取2014年2~11月就诊于我院的72例阴虚阳亢型原发性高血压患者,随机分为对照组和观察组,对照组予硝苯地平缓释片口服,观察组在硝苯地平缓释片基础上联合降压定眩片口服治疗高血压病,对比两组治疗前后的临床效果。结果:观察组临床治疗总有效率显著优于对照组,差异有统计学意义(P<0.05);治疗后两组收缩压、舒张压均显著降低,观察组降低血压效果明显优于对照组,组间比较,差异显著(P<0.05),雌二醇水平两组差异有统计学意义(P<0.05)。对照组对动态动脉硬化指数(AASI)无影响(P>0.05);观察组能够明显改善AASI(P<0.05)。结论:降压定眩片治疗阴虚阳亢型原发性高血压能够达到较满意治疗效果,能够显著改善阴虚阳亢型高血压患者各项临床症状,提高雌二醇水平,且对高血压病患者的AASI有明显改善作用。 Objective:To observe the curative effect mechanism of jiang ya ding xuan pian with extend release nifedipine tablets on pa-tients of essential hypertension(EH). Methods:A total of 72 EH patients were observed according to the diagnosis criteria.They were divided into two groups at random.The control group were treated by extend release nifedipine tablets,while patients in the treatment group were treated by jiang ya ding xuan pian.The course of treament lasted one months,then the curative effect and security of jiang ya ding xuan pian were observed.Results:In the treatment group,the clinical efficacy rate were more remarkably better than in control group,and the difference was significant between the two groups(P 0.01 or P 0.05).The level of SBP and DBP in treatment group were reduced more remarkably than in control group,The level of dihydrotheelin estradiol in treatment group were raised more remarkably than in con-trol group,The level of AASI in treatment group were improved more remarkably than in control group.Conclusions:Jiang ya ding xuan pian could improve the clinical symptoms and the level of dihydrotheelin estradiol;AASI about the EH patients.
出处 《内蒙古中医药》 2017年第21期1-3,共3页 Inner Mongolia Journal of Traditional Chinese Medicine
关键词 降压定眩片 阴虚阳亢 高血压病 动态动脉硬化指数 jiang ya ding xuan pian reducing Yin deficiency and yang hyperactivity essential hypertension dihydrotheelin estradiol Ambulatory Arterial Stiffness Index
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