摘要
目的探讨甲状腺乳头癌(PTC)颈部淋巴结转移患者超声特点及其与淋巴结转移的关系。方法回顾性分析经临床病理确诊为PTC的99例患者的超声诊断和病理结果资料,其中伴淋巴结转移的32例患者为淋巴结转移组,无淋巴结转移的67例患者为无淋巴结转移组。分析超声诊断PTC伴淋巴结转移的准确性、敏感度和特异度,单因素及多因素Logistic分析年龄、性别及超声征象与PTC伴淋巴结转移的关系。结果以临床病理检查为"金标准",超声诊断PTC伴淋巴结转移的准确性为88.89%,敏感度为81.25%,特异度为92.54%。淋巴结转移组年龄<50岁、微钙化、纵横比≥1、包膜受侵犯面积大、血供分级2~3级的几率高于无淋巴结转移组,差异有统计学意义(P<0.05)。结论超声征象中的癌结节增大、微钙化、包膜受侵犯面积大、血供分级为2~3级与PTC伴淋巴结转移密切相关。
Objective To investigate the ultrasound features of cervical lymph node metastasis of papillary thyroid carcinoma （PTC） and their relationship with lymph node metastasis. Methods The ultrasonic diagnosis and pathological data of 99 patients with PTC confirmed by clinical pathology were analyzed retrospectively. Among them, 32 patients with lymph node metastasis were divided into the lymph node metastasis group, and 67 cases without lymph node metastasis were divided into the non- lymph node metastasis group. The accuracy, sen-sitivity and specificity of ultrasound in the diagnosis of PTC with lymph node metastasis were analyzed, and the relationships between age, gender, ultrasound features, and PTC with lymph node metastasis were analyzed by univariate and multivariate analysis. Results With the results of clinical pathological examination as the golden standard, the accuracy, sensitivity and specificity of ultrasound diagnosis of PTC with lymph node metastasis were 88.89%, 81.25% and 92.54%, respectively. The probabilities of age 〈50 years old, micro-calcification, aspect ratio ≥1, capsule invasion area, and grade 2-3 blood supply of patients in the lymph node metastasis were higher than those in the non-lymph node metastasis group （P〈0.05）. Conclusion Ultrasound features such as enlargement of the tumor nodules, microcalcification, large invasion area of the membrane and grade 2 - 3 blood supply are closely related to PTC with lymph node metastasis.
出处
《肿瘤药学》
CAS
2018年第1期73-76,88,共5页
Anti-Tumor Pharmacy
