摘要
In order to provide basis for establishing a scientific and reasonable immune procedure against porcine contagious pleuropneumonia in pig farms, antibody dynamics in piglets inoculated with two vaccines against porcine contagious pleuropneumonia （ APP-1,2, 7 ） were detected. The result showed that average antibody blocking rate and antibody positive rate in piglets inoculated with two vaccines against porcine contagious pleuropneumonia exhibited similar variation trend. At 21 day after primary vaccination, average antibody blocking rate and antibody positive rate against porcine contagious pleuropneumonia in piglets reached the peak and then declined gradually. After secondary vaccination, average antibody blocking rate and antibody positive rate against porcine contagious pleuropneumonia in piglets increased gradually, which reached the second peak at 30 day after secondary vaccination （60 day after primary vaccination） ; subsequently, average antibody blocking rate declined gradually but still remained at a high level; antibody positive rate had little change. Average antibody blocking rate against APP-1 was slightly lower than the critical level of antibody protection at 44 day after primary vaccination ; antibody positive rate was slightly higher than the qualification rate at 37 day after primary vaccination; average antibody blocking rate against APP-7 was close to the critical level of antibody protection at 30 day after primary vaccina- tion, suggesting that piglets should be inoculated twice with polyvaccine against porcine contagious pleuropneumonia during the entire growth period, and the secondary vaccination should be performed at 30 -37 day after primary vaccination.
In order to provide basis for establishing a scientific and reasonable immune procedure against porcine contagious pleuropneumonia in pig farms, antibody dynamics in piglets inoculated with two vaccines against porcine contagious pleuropneumonia （ APP-1,2, 7 ） were detected. The result showed that average antibody blocking rate and antibody positive rate in piglets inoculated with two vaccines against porcine contagious pleuropneumonia exhibited similar variation trend. At 21 day after primary vaccination, average antibody blocking rate and antibody positive rate against porcine contagious pleuropneumonia in piglets reached the peak and then declined gradually. After secondary vaccination, average antibody blocking rate and antibody positive rate against porcine contagious pleuropneumonia in piglets increased gradually, which reached the second peak at 30 day after secondary vaccination （60 day after primary vaccination） ; subsequently, average antibody blocking rate declined gradually but still remained at a high level; antibody positive rate had little change. Average antibody blocking rate against APP-1 was slightly lower than the critical level of antibody protection at 44 day after primary vaccination ; antibody positive rate was slightly higher than the qualification rate at 37 day after primary vaccination; average antibody blocking rate against APP-7 was close to the critical level of antibody protection at 30 day after primary vaccina- tion, suggesting that piglets should be inoculated twice with polyvaccine against porcine contagious pleuropneumonia during the entire growth period, and the secondary vaccination should be performed at 30 -37 day after primary vaccination.
基金
Supported by National Natural Science Foundation of China(31560696)
Development Fund for Scientific Research Institutes in Hainan Province(KYYS-2014-32)
Special Fund for Integration of Production,Learning and Research of Hainan Province(cxy20150008)
