摘要
根据模拟移动床色谱技术的发展历程，对其工艺研发，包括异步切换模拟移动床和间歇式模拟移动床等新型操作工艺，以及模拟移动床色谱反应器等进行了综述。总结了近几年模拟移动床色谱技术在手性化合物拆分和糖醇分离中的应用研究进展；展望了模拟移动床色谱的研究方向和发展趋势。
In this paper, the development courses of simulated moving bed chromatography （SMB） are introduced. The operation modes of simulated moving bed chromatography are sum- marized including sequential simulated moving bed and Varicol. New types of simulated moving bed chromatographic reactors are discussed. The applications of SMB are reviewed in sugar alco- hol separation and chiral drugs separation. The research direction and development trend of simu- lated moving bed chromatography are prospected.
出处
《化学教育（中英文）》
CAS
北大核心
2018年第4期1-9,共9页
Chinese Journal of Chemical Education
基金
“十二五”国家重大科学仪器设备开发专项基金(2013YQ170525)
关键词
模拟移动床色谱
操作工艺
手性化合物
糖醇
simulated moving bed chromatography
operation mode
chiral drugs
saccha- rides
