摘要
目的观察二甲双胍+逍遥散加减治疗肥胖型2型糖尿病的临床效果。方法选取在医院就诊的肥胖型2型糖尿病(肝郁脾虚证)患者71例为研究对象,随机分为对照组35例和观察组36例。对照组单纯服用二甲双胍治疗,观察组采用二甲双胍+逍遥散加减治疗,观察比较2组治疗总有效率,治疗前后血糖、血脂、体质量指数(BMI)、腰臀比变化情况。结果观察组治疗总有效率为94.44%,高于对照组的77.14%(P<0.05);治疗后,2组空腹血糖(FPG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(Hb A1c)数值均有改善,观察组改善幅度大于对照组(P<0.05或P<0.01);治疗后,观察组总胆固醇(TC)、三酰甘油(TG)检测值低于对照组(P<0.05或P<0.01);治疗后,2组BMI、腰臀比数值较治疗前均降低,观察组BMI、腰臀比数值低于对照组(P均<0.01)。结论与单纯西药治疗相比,中西医结合治疗肥胖型2型糖尿病效果更佳,能够有效控制患者的血糖、血脂水平,减轻其体质量。
Objective To explore the effect of integrated meffonnin and Xiaoyaosan in the treatment of obesity type 2 diabetes mellitus. Methods 71 patients with obese type 2 diabetes mellitus in our hospital were randomly divided into control group（n =35） and study group（n = 36）. The control group was treated with mefformin,while the study group received metformin and Xiaoyaosan treatment. The total effective rate of treatment, blood sugar,blood lipids,body weight,and waist to hip ratio of two groups were observed and compared. Results The total effective rate of the study group was 94.44%, significantly higher than 77.14% of the control group （P 〈 0.05 ）. After the treatment, fasting plasma glucose （FPG） ,2b Postprandial Blood Glucose after 2 hours of the meal and HbA1 c in both groups were improved, and the improvement in the observation group was greater than that in the control group（P 〈0.05 or P 〈0.01 ）. The total cholesterol （TC） and triglyceride （TG） in the observation group were lower than those in the control group （P 〈 0.05 or P 〈 0.01 ）. After treatment, two groups of BMI,waist-hip ratio values were lower than before treatment. The BMI and waist-hip ratio in the observation group were lower than those in the control group （P 〈 0.01 ）. Conclusion Compared with the pure western medicine treatment, integrated traditional Chinese and western medicine produces better clinical efficacy for the treatment of obese type 2 diabetes, which can effectively control the patient＇s blood sugar, blood lipid levels, reduce their body weight.
出处
《临床合理用药杂志》
2018年第5期7-8,15,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
中西医结合
肥胖型
2型糖尿病
肝郁脾虚证
Integrated traditional Chinese and Western medicine
Obesity
Type 2 diabetes mellitus
Syndrome of stagnation of liver qi and spleen deficiency
