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布地奈德联合沙丁胺醇雾化吸入治疗小儿哮喘急性发作的临床效果分析及安全性评价 被引量:8

The clinical effect analysis and safety evaluation of the treatment of acute onset of asthma in children by budesonide combined with albuterol atomization inhalation
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摘要 目的观察将沙丁胺醇联合布地奈德应用于小儿哮喘急性发作的治疗中的临床疗效。方法根据不同的治疗方法将80例哮喘急性发作的患儿随机分为两组,各40例。其中对照组的主要治疗药物为沙丁胺醇,而沙丁胺醇与布地奈德则为研究组的主要治疗药物,对比分析两组的临床疗效。结果对照组和研究组的治疗总有效率分别为77.5%和95.00%,两组的总有效率比较,对照组显著低于研究组,差异有统计学意义(P<0.05)。两组患儿的不良反应发生率分别为10.00%、12.50%,差异无统计学意义。结论布地奈德联合沙丁胺醇雾化吸入治疗可有效改善患儿的病情,且安全性较高,对小儿哮喘急性发作的治疗具有显著的临床价值。 Objective To observe the clinical effect of albuterol combined with budesonide in the treatment of acute asthma attack in children.Methods 80 patients with acute attack of asthma were randomly divided into two groups with 40 cases.The main therapeutic agents in the control group were albuterol,while albuterol and budesonide were the main therapeutic agents for the research group,and the clinical efficacy of the two groups was compared and analyzed.Results The total effective rate of treatment in the control group was 77.5% and 95.00% respectively.The total effective comparison of the two groups was significantly lower than that in the control group,the difference was statistically significant(P<0.05).The incidence rate of adverse reactions in both groups was 10.00% and 12.50% respectively,and the difference was not statistically significant.Conclusion The inhalation of budesonide combined with albuterol atomization inhalation can effectively improve the condition of the children,and the safety is high,and the treatment of acute asthma attacks in children has significant clinical value.
出处 《当代医学》 2018年第6期51-53,共3页 Contemporary Medicine
关键词 小儿哮喘急性发作 雾化吸入 布地奈德 沙丁胺醇 Acute onset of asthma in children Atomization inhalation Budesonide Albuterol
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